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儿童慢性鼻-鼻窦炎伴鼻息肉患者功能性鼻内镜鼻窦手术的长期疗效。

Long-term results of functional endoscopic sinus surgery in children with chronic rhinosinusitis with nasal polyps.

出版信息

Rhinology. 2013 Dec;51(4):328-34. doi: 10.4193/Rhino13.079.

Abstract

BACKGROUND

Chronic rhinosinusitis with nasal polyps (CRSwNP) is rare in children and has a major impact on Quality of Life (QoL). Functional endoscopic sinus surgery (FESS) has proven to be an effective treatment, but it is still unclear what long-term outcomes are in children with CRSwNP. The objective of this study was to assess long-term results of FESS in children with CRSwNP.

METHODOLOGY

We performed a combined prospective and retrospective study. A QoL questionnaire was send to all children with CRSwNP who received FESS between the year 2000-2010. Almost half of these children also filled in this questionnaire preoperatively.

RESULTS

Forty-four Children underwent FESS. From 18 patients, we also prospectively collected preoperative QoL questionnaires. The mean follow-up period was 4.0 years (+- 2.9). The mean age at surgery was 13 years (+-2.9). Of these children, 9 had CF and 10 children asthma. R-SOM scores showed a significant improvement both in general symptoms as well as several different domains when comparing pre- and postoperative questionnaires. Only 5 of 44 patients needed a subsequent intervention. In children with CF this was 3 of 9.

CONCLUSION

This study demonstrates that long-term results of FESS in children with CRSwNP are good. QoL has improved significantly, especially in nasal symptoms, showing that FESS is a good treatment in children with CRSwNP. Furthermore, even children with CF show good results.

摘要

背景

儿童慢性鼻-鼻窦炎伴鼻息肉(CRSwNP)较为罕见,对生活质量(QoL)有重大影响。功能性内镜鼻窦手术(FESS)已被证实为一种有效的治疗方法,但儿童 CRSwNP 的长期疗效仍不明确。本研究旨在评估 FESS 治疗儿童 CRSwNP 的长期疗效。

方法

我们进行了一项前瞻性和回顾性相结合的研究。我们向所有在 2000 年至 2010 年间接受 FESS 的 CRSwNP 患儿发送了生活质量问卷。其中近一半患儿还在术前填写了该问卷。

结果

44 名患儿接受了 FESS。我们前瞻性地从 18 名患儿中收集了术前 QoL 问卷。平均随访时间为 4.0 年(+ - 2.9)。手术时的平均年龄为 13 岁(+ - 2.9)。这些患儿中,9 例为 CF,10 例为哮喘。R-SOM 评分显示,与术前相比,术后总体症状以及多个不同领域的评分均显著改善。44 例患儿中仅 5 例需要进一步干预。CF 患儿中为 3 例。

结论

本研究表明,FESS 治疗儿童 CRSwNP 的长期疗效良好。QoL 显著改善,尤其是鼻部症状,表明 FESS 是儿童 CRSwNP 的一种有效治疗方法。此外,即使是 CF 患儿也能取得良好的效果。

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