Tanveer Uzma, Gul Amna, Aqil Shakil
Department of Otolaryngology - Head and Neck Surgery, Liaquat National Hospital and Medical College, National Stadium Road, Karachi, 74800 Pakistan.
Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 3):1832-1836. doi: 10.1007/s12070-017-1218-y. Epub 2017 Oct 11.
To assess the incidence and recurrence of patients of allergic fungal sinusitis after administration of topical steroids for 24 months this is a cross-section study. Total 90 patients diagnosed with nasal pathology were enrolled from January 2011 to December 2015 at Liaquat National Hospital, various sign and symptoms were tabulated. Patients clinical, radiological and histopathological reports were analyzed. Post operative steroid dose and recurrence rate was noted. Post stratification, Chi-square test and Fisher's exact test was applied to see the association between CT Scan and endoscopic findings and recurrence considering value ≤ 0.05 as significant. Total 90 patients of either sex aged between 12 and 63 years fulfilled the inclusion criteria and were enrolled in the study. The results showed that among all study patients, 53(58.9%) were male and 37(41.1%) were female. Common presenting symptoms included nasal obstruction, nasal discharge & headache followed by proptosis. From 90 cases, 73(81.2%) had chronic rhinosinusitis and 17(18.9%) cases had Aspergillus. Postoperatively patients were given topical steroids and recurrence was seen in twelve (17.8%). All were aspergillus positive. The incidence of AFRS is (17) 18.9% of CRS which is slightly higher as reported in previous literature. Endoscopic finding may differ from CT scan finding. Patients presented with CRS should receive steroids for at least 2 years to prevent recurrence.
为评估局部使用类固醇药物24个月后变应性真菌性鼻窦炎患者的发病率和复发情况,本研究为横断面研究。2011年1月至2015年12月期间,从利亚卡特国家医院招募了90例被诊断为鼻腔疾病的患者,将各种体征和症状制成表格。分析患者的临床、放射学和组织病理学报告。记录术后类固醇剂量和复发率。分层后,应用卡方检验和Fisher精确检验,以0.05为显著性水平,观察CT扫描与内镜检查结果之间的关联以及复发情况。共有90例年龄在12至63岁之间的男女患者符合纳入标准并被纳入研究。结果显示,在所有研究患者中,男性53例(58.9%),女性37例(41.1%)。常见的症状包括鼻塞、流涕和头痛,其次是眼球突出。90例患者中,73例(81.2%)患有慢性鼻窦炎,17例(18.9%)患有曲霉菌病。术后患者接受局部类固醇治疗,12例(17.8%)出现复发。所有复发患者曲霉菌检测均为阳性。变应性真菌性鼻窦炎的发病率为慢性鼻窦炎患者的18.9%(17例),略高于以往文献报道。内镜检查结果可能与CT扫描结果不同。患有慢性鼻窦炎的患者应接受至少2年的类固醇治疗以预防复发。