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Vascularization of the pancreas: an evolving role from embryogenesis to adulthood.

作者信息

Duvillié Bertrand

机构信息

INSERM U845, Research Center Growth and Signalling, Paris, France.

出版信息

Diabetes. 2013 Dec;62(12):4004-5. doi: 10.2337/db13-1421.

DOI:10.2337/db13-1421
PMID:24264402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3837028/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f26c/3837028/c34569eb6567/4004fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f26c/3837028/c34569eb6567/4004fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f26c/3837028/c34569eb6567/4004fig1.jpg

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本文引用的文献

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Conditional hypovascularization and hypoxia in islets do not overtly influence adult β-cell mass or function.胰岛内的条件性低血管化和缺氧不会明显影响成年β细胞的质量或功能。
Diabetes. 2013 Dec;62(12):4165-73. doi: 10.2337/db12-1827. Epub 2013 Aug 23.
2
Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets.血管内皮生长因子-a 和胰岛血管化对于胰岛的发育是必需的,但对于成年胰岛则不是必需的。
Diabetes. 2013 Dec;62(12):4154-64. doi: 10.2337/db13-0071. Epub 2013 Jul 24.
3
Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function.
Rev Endocr Metab Disord. 2021 Jun;22(2):421-451. doi: 10.1007/s11154-020-09606-0. Epub 2020 Oct 14.
4
Conformal Coating of Stem Cell-Derived Islets for β Cell Replacement in Type 1 Diabetes.干细胞衍生胰岛的包被用于 1 型糖尿病的β细胞替代
Stem Cell Reports. 2020 Jan 14;14(1):91-104. doi: 10.1016/j.stemcr.2019.11.004. Epub 2019 Dec 12.
5
Pleiotropic roles of the insulin-like growth factor axis in type 1 diabetes.胰岛素样生长因子轴在 1 型糖尿病中的多效作用。
Curr Opin Endocrinol Diabetes Obes. 2019 Aug;26(4):188-194. doi: 10.1097/MED.0000000000000484.
6
von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-α and VEGF-A upregulation.小鼠胰腺祖细胞中冯·希佩尔-林道基因的破坏及其对体内内分泌分化的影响:缺氧诱导因子1-α和血管内皮生长因子-A上调的重要性
Diabetologia. 2014 Nov;57(11):2348-56. doi: 10.1007/s00125-014-3365-y. Epub 2014 Sep 4.
7
Long-term function of islets encapsulated in a redesigned alginate microcapsule construct in omentum pouches of immune-competent diabetic rats.在免疫活性糖尿病大鼠的大网膜囊袋中,重新设计的藻酸盐微胶囊构建体中包封的胰岛的长期功能。
Pancreas. 2014 May;43(4):605-13. doi: 10.1097/MPA.0000000000000107.
VEGFR-2 抑制可通过消除胰岛炎和恢复胰岛功能逆转 NOD 小鼠的 1 型糖尿病。
Diabetes. 2013 Aug;62(8):2870-8. doi: 10.2337/db12-1619. Epub 2013 Jul 8.
4
Vascular instruction of pancreas development.血管对胰腺发育的指导作用。
Development. 2012 Aug;139(16):2833-43. doi: 10.1242/dev.065953.
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HIF1α and pancreatic β-cell development.缺氧诱导因子 1α 与胰腺 β 细胞发育。
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Development. 2011 Nov;138(21):4743-52. doi: 10.1242/dev.066548. Epub 2011 Sep 28.
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J Clin Invest. 2010 Jun;120(6):2171-83. doi: 10.1172/JCI35846. Epub 2010 May 3.
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Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha.氧张力通过缺氧诱导因子 1α调节胰腺β细胞分化。
Diabetes. 2010 Mar;59(3):662-9. doi: 10.2337/db09-0891. Epub 2009 Dec 15.
9
Oxygen: a master regulator of pancreatic development?氧气:胰腺发育的主要调节因子?
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Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.胰腺β细胞中冯·希佩尔-林道基因的缺失会损害小鼠的葡萄糖稳态。
J Clin Invest. 2009 Jan;119(1):125-35. doi: 10.1172/JCI26934. Epub 2008 Dec 8.