在用两性霉素 B 治疗后，一例血清阴性儿童因感染暹罗利什曼原虫而出现内脏利什曼病复发。
Recurrences of visceral leishmaniasis caused by Leishmania siamensis after treatment with amphotericin B in a seronegative child.
机构信息
Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand.
出版信息
Am J Trop Med Hyg. 2014 Jan;90(1):40-2. doi: 10.4269/ajtmh.13-0398. Epub 2013 Nov 25.
Abstract
We report the first case of visceral leishmaniasis caused by Leishmania siamensis in a seronegative child. She was treated with amphotericin B at 1 mg/kg/day for 3 weeks; however, recurrences occurred twice. The patient was cured after the administration of amphotericin B for 5 weeks and monthly prophylaxis for 6 months.
摘要
我们报告了首例由 siamensis 利什曼原虫引起的内脏利什曼病的病例，该病例发生于一名血清阴性的儿童。患儿接受了 1 毫克/公斤/天的两性霉素 B 治疗 3 周，但仍复发了 2 次。给予 5 周两性霉素 B 治疗和 6 个月每月预防治疗后，患儿痊愈。
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