Rodríguez-Quintanilla Karina Alejandra, Lavalle-González Fernando Javier, Mancillas-Adame Leonardo Guadalupe, Zapata-Garrido Alfonso Javier, Villarreal-Pérez Jesús Zacarías, Tamez-Pérez Héctor Eloy
Departamento de Medicina Interna, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Servicio de Endocrinología, Departamento de Medicina Interna, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico; Departamento de Medicina Interna, Hospital Universitario Dr. José Eleuterio González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Arch Cardiol Mex. 2013 Oct-Dec;83(4):237-43. doi: 10.1016/j.acmx.2013.08.001. Epub 2013 Nov 25.
Diabetes mellitus is an independent risk factor for cardiovascular disease.
To compare the efficacy of devices for continuous glucose monitoring and capillary glucose monitoring in hospitalized patients with acute coronary syndrome using the following parameters: time to achieve normoglycemia, period of time in normoglycemia, and episodes of hypoglycemia.
We performed a pilot, non-randomized, unblinded clinical trial that included 16 patients with acute coronary artery syndrome, a capillary or venous blood glucose ≥ 140 mg/dl, and treatment with a continuous infusion of fast acting human insulin. These patients were randomized into 2 groups: a conventional group, in which capillary measurement and recording as well as insulin adjustment were made every 4h, and an intervention group, in which measurement and recording as well as insulin adjustment were made every hour with a subcutaneous continuous monitoring system. Student's t-test was applied for mean differences and the X(2) test for qualitative variables.
We observed a statistically significant difference in the mean time for achieving normoglycemia, favoring the conventional group with a P = 0.02.
Continuous monitoring systems are as useful as capillary monitoring for achieving normoglycemia.
糖尿病是心血管疾病的独立危险因素。
使用以下参数比较住院急性冠状动脉综合征患者中持续葡萄糖监测设备与毛细血管葡萄糖监测的疗效：达到正常血糖的时间、处于正常血糖的时间段以及低血糖发作次数。
我们进行了一项前瞻性、非随机、非盲法临床试验，纳入了16例急性冠状动脉综合征患者，其毛细血管或静脉血糖≥140mg/dl，并接受速效人胰岛素持续静脉输注治疗。这些患者被随机分为两组：常规组，每4小时进行一次毛细血管测量、记录以及胰岛素调整；干预组，使用皮下连续监测系统每小时进行测量、记录以及胰岛素调整。采用学生t检验分析均值差异，采用X²检验分析定性变量。
我们观察到达到正常血糖的平均时间存在统计学显著差异，常规组更具优势，P = 0.02。
在实现正常血糖方面，连续监测系统与毛细血管监测同样有用。
