Doctorado en Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Xochimilco, México D.F. 04960, Mexico.
Molecules. 2013 Nov 25;18(12):14597-612. doi: 10.3390/molecules181214597.
In Mexico black cherry (Prunus serotina Ehrh.) fruits are consumed fresh, dried or prepared in jam. Considering the evidence that has linked intake of fruits and vegetables rich in polyphenols to cardiovascular risk reduction, the aim of this study was to characterize the phenolic profile of black cherry fruits and to determine their antioxidant, vasorelaxant and antihypertensive effects. The proximate composition and mineral contents of these fruits were also assessed. Black cherry fruits possess a high content of phenolic compounds and display a significant antioxidant capacity. High-performance liquid chromatography/mass spectrometric analysis indicated that hyperoside, anthocyanins and chlorogenic acid were the main phenolic compounds found in these fruits. The black cherry aqueous extract elicited a concentration-dependent relaxation of aortic rings and induced a significant reduction on systolic blood pressure in L-NAME induced hypertensive rats after four weeks of treatment. Proximate analysis showed that black cherry fruits have high sugar, protein, and potassium contents. The results derived from this study indicate that black cherry fruits contain phenolic compounds which elicit significant antioxidant and antihypertensive effects. These findings suggest that these fruits might be considered as functional foods useful for the prevention and treatment of cardiovascular diseases.
在墨西哥，黑樱桃（Prunus serotina Ehrh.）果实既可以新鲜食用，也可以晒干后食用，或者制成果酱。鉴于有证据表明，摄入富含多酚的水果和蔬菜与降低心血管疾病风险有关，本研究旨在对黑樱桃果实的酚类物质组成进行分析，并确定其抗氧化、血管舒张和降压作用。此外，还对这些水果的基本成分和矿物质含量进行了评估。黑樱桃果实含有丰富的酚类化合物，具有显著的抗氧化能力。高效液相色谱/质谱分析表明，这些果实中的主要酚类化合物是金丝桃苷、花青素和绿原酸。黑樱桃水提物可引起主动脉环浓度依赖性舒张，并在 4 周的治疗后显著降低 L-NAME 诱导的高血压大鼠的收缩压。基本成分分析表明，黑樱桃果实含有丰富的糖、蛋白质和钾。本研究结果表明，黑樱桃果实含有可发挥显著抗氧化和降压作用的酚类化合物。这些发现表明，这些水果可能被视为具有预防和治疗心血管疾病的功能性食品。
