• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

脂多糖的O抗原链对大肠杆菌外膜蛋白作为噬菌体和大肠杆菌素受体的屏蔽作用。

Shielding of Escherichia coli outer membrane proteins as receptors for bacteriophages and colicins by O-antigenic chains of lipopolysaccharide.

作者信息

van der Ley P, de Graaff P, Tommassen J

出版信息

J Bacteriol. 1986 Oct;168(1):449-51. doi: 10.1128/jb.168.1.449-451.1986.

DOI:10.1128/jb.168.1.449-451.1986
PMID:2428812
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC213476/
Abstract

The accessibility of several outer membrane proteins for bacteriophages and colicins in isogenic smooth and rough Escherichia coli strains was investigated. The results show that O antigen carrying lipopolysaccharide is able to prevent access of all phages and colicins tested to their outer membrane protein receptors.

摘要

研究了几种外膜蛋白在同基因光滑型和粗糙型大肠杆菌菌株中对噬菌体和大肠杆菌素的可及性。结果表明，携带脂多糖的O抗原能够阻止所有测试的噬菌体和大肠杆菌素接近其外膜蛋白受体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e04/213476/55af4ea3314b/jbacter00203-0460-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e04/213476/55af4ea3314b/jbacter00203-0460-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e04/213476/55af4ea3314b/jbacter00203-0460-a.jpg

相似文献

1
Shielding of Escherichia coli outer membrane proteins as receptors for bacteriophages and colicins by O-antigenic chains of lipopolysaccharide.脂多糖的O抗原链对大肠杆菌外膜蛋白作为噬菌体和大肠杆菌素受体的屏蔽作用。
J Bacteriol. 1986 Oct;168(1):449-51. doi: 10.1128/jb.168.1.449-451.1986.
2
The tol gene products and the import of macromolecules into Escherichia coli.tol基因产物与大分子物质导入大肠杆菌的过程
Mol Microbiol. 1991 May;5(5):1005-11. doi: 10.1111/j.1365-2958.1991.tb01873.x.
3
Specific regions of Escherichia coli OmpF protein involved in antigenic and colicin receptor sites and in stable trimerization.
J Bacteriol. 1993 May;175(9):2754-7. doi: 10.1128/jb.175.9.2754-2757.1993.
4
Pumping iron through cell membranes.通过细胞膜输送铁元素。
Science. 1998 Dec 18;282(5397):2202-3. doi: 10.1126/science.282.5397.2202.
5
Comparison of the uptake systems for the entry of various BtuB group colicins into Escherichia coli.
J Gen Microbiol. 1989 Dec;135(12):3413-20. doi: 10.1099/00221287-135-12-3413.
6
A new colicin that adsorbs to outer-membrane protein Tsx but is dependent on the tonB instead of the tolQ membrane transport system.
J Gen Microbiol. 1992 Dec;138(12):2721-4. doi: 10.1099/00221287-138-12-2721.
7
Energy-dependent receptor activities of Escherichia coli K-12: mutated TonB proteins alter FhuA receptor activities to phages T5, T1, phi 80 and to colicin M.大肠杆菌K-12的能量依赖性受体活性：突变的TonB蛋白改变了FhuA受体对噬菌体T5、T1、φ80以及对大肠菌素M的活性。
FEMS Microbiol Lett. 1994 Jun 1;119(1-2):71-6. doi: 10.1111/j.1574-6968.1994.tb06869.x.
8
The TolC protein of Escherichia coli serves as a cell-surface receptor for the newly characterized TLS bacteriophage.大肠杆菌的TolC蛋白充当新鉴定的TLS噬菌体的细胞表面受体。
J Mol Biol. 2001 May 11;308(4):579-85. doi: 10.1006/jmbi.2001.4578.
9
Binding of the immunity protein inactivates colicin M.免疫蛋白的结合使大肠杆菌素M失活。
Mol Microbiol. 1991 May;5(5):1105-11. doi: 10.1111/j.1365-2958.1991.tb01883.x.
10
Properties of the FhuA channel in the Escherichia coli outer membrane after deletion of FhuA portions within and outside the predicted gating loop.在预测的门控环内外缺失FhuA部分后，大肠杆菌外膜中FhuA通道的特性。
J Bacteriol. 1996 Dec;178(23):6913-20. doi: 10.1128/jb.178.23.6913-6920.1996.

引用本文的文献

1
Completing the BASEL phage collection to unlock hidden diversity for systematic exploration of phage-host interactions.完善巴塞尔噬菌体库，以解锁隐藏的多样性，用于系统探索噬菌体 - 宿主相互作用。
PLoS Biol. 2025 Apr 7;23(4):e3003063. doi: 10.1371/journal.pbio.3003063. eCollection 2025 Apr.
2
Bacterial Virus Forcing of Bacterial O-Antigen Shields: Lessons from Coliphages.细菌病毒对细菌 O 抗原盾的强制作用：来自噬菌体的教训。
Int J Mol Sci. 2023 Dec 12;24(24):17390. doi: 10.3390/ijms242417390.
3
Enteric Populations of are Likely to be Resistant to Phages Due to O Antigen Expression.

本文引用的文献

1
The ultimate localization of an outer membrane protein of Escherichia coli K-12 is not determined by the signal sequence.大肠杆菌K-12外膜蛋白的最终定位不是由信号序列决定的。
EMBO J. 1983;2(8):1275-9. doi: 10.1002/j.1460-2075.1983.tb01581.x.
2
Resistance of gram-negative bacteria to purified bactericidal leukocyte proteins: relation to binding and bacterial lipopolysaccharide structure.革兰氏阴性菌对纯化杀菌白细胞蛋白的抗性：与结合及细菌脂多糖结构的关系。
J Clin Invest. 1980 Mar;65(3):619-28. doi: 10.1172/JCI109707.
3
The ins and outs of colicins. Part I: Production, and translocation across membranes.
由于O抗原的表达，肠道中的[具体内容缺失]群体可能对噬菌体具有抗性。
bioRxiv. 2024 Jul 2:2023.11.08.566299. doi: 10.1101/2023.11.08.566299.
4
Combining lipid-mimicking-enabled transition metal and enzyme-mediated catalysis at the cell surface of .在……的细胞表面结合具有模拟脂质功能的过渡金属和酶介导的催化作用。 （原句似乎不完整）
Chem Sci. 2023 Oct 6;14(42):11896-11906. doi: 10.1039/d3sc02960c. eCollection 2023 Nov 1.
5
Stepwise Evolution of E. coli C and ΦX174 Reveals Unexpected Lipopolysaccharide (LPS) Diversity.大肠杆菌 C 和 ΦX174 的逐步进化揭示了意想不到的脂多糖 (LPS) 多样性。
Mol Biol Evol. 2023 Jul 5;40(7). doi: 10.1093/molbev/msad154.
6
Host Range Expansion of Phage Sf6 Evolves through Point Mutations in the Tailspike.噬菌体 Sf6 通过尾丝蛋白的点突变实现宿主范围扩张。
J Virol. 2022 Aug 24;96(16):e0092922. doi: 10.1128/jvi.00929-22. Epub 2022 Jul 27.
7
Phosphonate production by marine microbes: Exploring new sources and potential function.海洋微生物产生的膦酸盐：探索新的来源和潜在功能。
Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2113386119. doi: 10.1073/pnas.2113386119. Epub 2022 Mar 7.
8
A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants.经合理设计的口服疫苗可在鼠类肠道中诱导免疫球蛋白 A，从而引导减毒沙门氏菌变异株的演变。
Nat Microbiol. 2021 Jul;6(7):830-841. doi: 10.1038/s41564-021-00911-1. Epub 2021 May 27.
9
O antigen restricts lysogenization of non-O157 Escherichia coli strains by Stx-converting bacteriophage phi24B.O 抗原限制 Stx 噬菌体 phi24B 对非 O157 大肠杆菌菌株的溶原化。
Sci Rep. 2021 Feb 4;11(1):3035. doi: 10.1038/s41598-021-82422-x.
10
Mucoidy, a general mechanism for maintaining lytic phage in populations of bacteria.粘液层形成，一种维持噬菌体能在细菌群体中持续存在的通用机制。
FEMS Microbiol Ecol. 2020 Oct 2;96(10). doi: 10.1093/femsec/fiaa162.
大肠杆菌素的来龙去脉。第一部分：产生及跨膜转运。
Microbiol Sci. 1984 Oct;1(7):168-75.
4
Cloning and expression in Escherichia coli K-12 of the structural gene for outer membrane PhoE protein from Enterobacter cloacae.阴沟肠杆菌外膜PhoE蛋白结构基因在大肠杆菌K-12中的克隆与表达。
Gene. 1984 Dec;32(1-2):107-15. doi: 10.1016/0378-1119(84)90038-6.
5
Bactericidal and bacteriolytic activity of serum against gram-negative bacteria.血清对革兰氏阴性菌的杀菌和溶菌活性。
Microbiol Rev. 1983 Mar;47(1):46-83. doi: 10.1128/mr.47.1.46-83.1983.
6
Molecular architecture and functioning of the outer membrane of Escherichia coli and other gram-negative bacteria.大肠杆菌及其他革兰氏阴性菌外膜的分子结构与功能
Biochim Biophys Acta. 1983 Mar 21;737(1):51-115. doi: 10.1016/0304-4157(83)90014-x.
7
DNA sequence analysis of the Serratia marcescens ompA gene: implications for the organisation of an enterobacterial outer membrane protein.粘质沙雷氏菌ompA基因的DNA序列分析：对肠杆菌外膜蛋白组织的影响
Mol Gen Genet. 1984;195(1-2):321-8. doi: 10.1007/BF00332766.
8
Antigenic polymorphism of the LamB protein among members of the family Enterobacteriaceae.
J Bacteriol. 1985 Jul;163(1):106-10. doi: 10.1128/jb.163.1.106-110.1985.
9
O-antigenic chains of lipopolysaccharide prevent binding of antibody molecules to an outer membrane pore protein in Enterobacteriaceae.脂多糖的O抗原链可阻止抗体分子与肠杆菌科细菌外膜孔蛋白的结合。
Microb Pathog. 1986 Feb;1(1):43-9. doi: 10.1016/0882-4010(86)90030-6.
10
Occurrence of the bacteriophage lambda receptor in some enterobacteriaceae.某些肠杆菌科细菌中λ噬菌体受体的存在情况。
J Virol. 1975 Apr;15(4):679-85. doi: 10.1128/JVI.15.4.679-685.1975.