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巴西圣路易斯市社区获得性尿路感染中产超广谱β-内酰胺酶肠杆菌科细菌。

Extended-spectrum β-lactamase-producing enterobacteriaceae in community-acquired urinary tract infections in São Luís, Brazil.

机构信息

Universidade Federal do Maranhão, São Luís, MA, Brazil.

出版信息

Braz J Microbiol. 2013 Oct 30;44(2):469-71. doi: 10.1590/S1517-83822013005000038. eCollection 2013.

DOI:10.1590/S1517-83822013005000038
PMID:24294239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3833145/
Abstract

The number of ESBL-producing Enterobacteriaceae in community-acquired urinary tract infections worldwide is probably underestimated because of the technical difficulties encountered with their detection. In this study, out of 5,672 urine samples analyzed, 916 were positive for uropathogens, 472 of them being enterobacteria of which 7.6% produced β-lactamases. Analysis of the isolated from 36 patients showed a high level of antibiotic resistance, with 52.7% and 80.5% of isolates expressing bla TEM and bla CTX-M, respectively.

摘要

在全球范围内，由于检测技术上的困难，社区获得性尿路感染中产生 ESBL 的肠杆菌科的数量可能被低估了。在这项研究中，在分析的 5672 个尿样中，有 916 个为尿病原体阳性，其中 472 个为肠杆菌，其中 7.6%产生了β-内酰胺酶。对 36 名患者分离出的菌株进行分析显示出高度的抗生素耐药性，分别有 52.7%和 80.5%的分离株表达 blaTEM 和 blaCTX-M。

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本文引用的文献

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Community-onset bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli: risk factors and prognosis.产超广谱β-内酰胺酶大肠埃希菌引起的社区获得性菌血症：危险因素和预后。
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Extended spectrum beta-lactamases (ESBL) in Escherichia coli and Klebsiella pneumoniae: trends in the hospital and community settings.大肠埃希菌和肺炎克雷伯菌中的超广谱β-内酰胺酶（ESBL）：医院和社区环境中的趋势
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CTX-M beta-lactamases in Escherichia coli from community-acquired urinary tract infections, Cambodia.柬埔寨社区获得性尿路感染患者大肠埃希菌中的CTX-Mβ-内酰胺酶
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Molecular characteristics of extended-spectrum-beta-lactamase-producing Escherichia coli isolates causing bacteremia in the Calgary Health Region from 2000 to 2007: emergence of clone ST131 as a cause of community-acquired infections.2000年至2007年在卡尔加里健康区域引起菌血症的产超广谱β-内酰胺酶大肠杆菌分离株的分子特征：克隆ST131作为社区获得性感染病因的出现
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Extended-spectrum beta-lactamase-producing Enterobacteriaceae: an emerging public-health concern.产超广谱β-内酰胺酶肠杆菌科细菌：一个新出现的公共卫生问题。
Lancet Infect Dis. 2008 Mar;8(3):159-66. doi: 10.1016/S1473-3099(08)70041-0.
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Community emergence of CTX-M type extended-spectrum beta-lactamases among urinary Escherichia coli from women.女性尿液中大肠埃希菌CTX-M型超广谱β-内酰胺酶的社区出现情况
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J Antimicrob Chemother. 2006 Apr;57(4):780-3. doi: 10.1093/jac/dkl035. Epub 2006 Feb 21.