• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

牛对脂阿拉伯甘露聚糖疫苗接种和感染结核分枝杆菌的反应。

Bovine response to lipoarabinomannan vaccination and challenge with Mycobacterium paratuberculosis.

机构信息

Cátedra de Inmunología, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Buenos Aires, Argentina.

出版信息

Braz J Microbiol. 2013 Oct 30;44(2):511-4. doi: 10.1590/S1517-83822013000200029. eCollection 2013.

DOI:10.1590/S1517-83822013000200029
PMID:24294248
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3833154/
Abstract

This study aimed to evaluate the immune response in bovines following immunization with a mycobaterial Lipoarabinomannan extract (LAMe) and the effect of Map challenge. LAMe vaccine induced specific antibody levels that diminished after the challenge and affected Map excretion at least for 100 days thereafter.

摘要

本研究旨在评估牛在接种分枝杆菌阿拉伯甘露聚糖提取物（LAMe）后的免疫反应以及 Map 挑战的影响。LAMe 疫苗诱导产生了特异性抗体水平，这些水平在挑战后下降，并在随后至少 100 天内影响 Map 的排泄。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c847/3833154/ca87d3066aa2/bjm-44-511-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c847/3833154/323b24bd2162/bjm-44-511-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c847/3833154/ca87d3066aa2/bjm-44-511-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c847/3833154/323b24bd2162/bjm-44-511-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c847/3833154/ca87d3066aa2/bjm-44-511-g002.jpg

相似文献

1
Bovine response to lipoarabinomannan vaccination and challenge with Mycobacterium paratuberculosis.牛对脂阿拉伯甘露聚糖疫苗接种和感染结核分枝杆菌的反应。
Braz J Microbiol. 2013 Oct 30;44(2):511-4. doi: 10.1590/S1517-83822013000200029. eCollection 2013.
2
Cell-mediated and humoral immune responses after immunization of calves with a recombinant multiantigenic Mycobacterium avium subsp. paratuberculosis subunit vaccine at different ages.不同年龄段的犊牛用重组多抗原禽分枝杆菌副结核亚种亚单位疫苗免疫后的细胞介导免疫和体液免疫反应。
Clin Vaccine Immunol. 2013 Apr;20(4):551-8. doi: 10.1128/CVI.05574-11. Epub 2013 Feb 6.
3
Serologic enzyme-linked immunosorbent assay responses of calves vaccinated with a killed Mycobacterium paratuberculosis vaccine.用灭活副结核分枝杆菌疫苗接种的犊牛的血清学酶联免疫吸附测定反应。
Am J Vet Res. 1991 Aug;52(8):1197-200.
4
Mycobacterium avium subsp. paratuberculosis antibody response, fecal shedding, and antibody cross-reactivity to Mycobacterium bovis in M. avium subsp. paratuberculosis-infected cattle herds vaccinated against Johne's disease.在接种了副结核分枝杆菌疫苗以预防副结核病的副结核分枝杆菌感染牛群中，副结核分枝杆菌抗体反应、粪便排菌情况以及对牛分枝杆菌的抗体交叉反应性。
Clin Vaccine Immunol. 2014 May;21(5):698-703. doi: 10.1128/CVI.00032-14. Epub 2014 Mar 12.
5
Differential changes in heat shock protein-, lipoarabinomannan-, and purified protein derivative-specific immunoglobulin G1 and G2 isotype responses during bovine Mycobacterium avium subsp. paratuberculosis infection.牛副结核分枝杆菌亚种感染期间，热休克蛋白、脂阿拉伯甘露聚糖和纯化蛋白衍生物特异性免疫球蛋白G1和G2同种型反应的差异变化。
Infect Immun. 2001 Mar;69(3):1492-8. doi: 10.1128/IAI.69.3.1492-1498.2001.
6
Characterization of the long-term immune response to vaccination against Mycobacterium avium subsp. paratuberculosis in Danish dairy cows.丹麦奶牛针对副结核分枝杆菌亚种疫苗接种的长期免疫反应特征
Vet Immunol Immunopathol. 2012 Jan 15;145(1-2):316-22. doi: 10.1016/j.vetimm.2011.11.021. Epub 2011 Dec 3.
7
Evaluation of the long-term immune response in cattle after vaccination against paratuberculosis in two Dutch dairy herds.荷兰两个奶牛场接种副结核病疫苗后牛群长期免疫反应的评估。
Vet Microbiol. 2002 May 1;86(3):269-78. doi: 10.1016/s0378-1135(02)00006-8.
8
Mediation of host immune responses after immunization of neonatal calves with a heat-killed Mycobacterium avium subsp. paratuberculosis vaccine.新生犊牛用热灭活副结核分枝杆菌疫苗免疫后宿主免疫反应的介导作用。
Clin Vaccine Immunol. 2011 Dec;18(12):2079-89. doi: 10.1128/CVI.05421-11. Epub 2011 Oct 26.
9
Cellular and humoral immune responses in sheep vaccinated with candidate antigens MAP2698c and MAP3567 from Mycobacterium avium subspecies paratuberculosis.用副结核分枝杆菌候选抗原MAP2698c和MAP3567免疫的绵羊的细胞免疫和体液免疫反应。
Front Cell Infect Microbiol. 2014 Jul 16;4:93. doi: 10.3389/fcimb.2014.00093. eCollection 2014.
10
The humoral immune response is essential for successful vaccine protection against paratuberculosis in sheep.体液免疫应答对于成功预防绵羊副结核病疫苗保护至关重要。
BMC Vet Res. 2019 Jul 2;15(1):223. doi: 10.1186/s12917-019-1972-z.

引用本文的文献

1
Lipoarabinomannan in Active and Passive Protection Against Tuberculosis.脂阿拉伯甘露聚糖在结核病主动和被动保护中的作用。
Front Immunol. 2019 Sep 11;10:1968. doi: 10.3389/fimmu.2019.01968. eCollection 2019.
2
Pathogenesis, Molecular Genetics, and Genomics of subsp. , the Etiologic Agent of Johne's Disease.副结核分枝杆菌（约翰氏病的病原体）的发病机制、分子遗传学和基因组学
Front Vet Sci. 2017 Nov 6;4:187. doi: 10.3389/fvets.2017.00187. eCollection 2017.

本文引用的文献

1
Detection of Bovine IgG Isotypes in a PPA-ELISA for Johne's Disease Diagnosis in Infected Herds.在用于感染牛群中副结核诊断的PPA-ELISA中检测牛IgG同种型
Vet Med Int. 2012;2012:145318. doi: 10.1155/2012/145318. Epub 2012 Jun 26.
2
Paratuberculosis control: a review with a focus on vaccination.副结核病控制：以疫苗接种为重点的综述
J Immune Based Ther Vaccines. 2011 Oct 31;9:8. doi: 10.1186/1476-8518-9-8.
3
Mediation of host immune responses after immunization of neonatal calves with a heat-killed Mycobacterium avium subsp. paratuberculosis vaccine.
新生犊牛用热灭活副结核分枝杆菌疫苗免疫后宿主免疫反应的介导作用。
Clin Vaccine Immunol. 2011 Dec;18(12):2079-89. doi: 10.1128/CVI.05421-11. Epub 2011 Oct 26.
4
Antibodies Induced by Lipoarabinomannan in Bovines: Characterization and Effects on the Interaction between Mycobacterium Avium Subsp. Paratuberculosis and Macrophages In Vitro.脂阿拉伯甘露聚糖诱导牛产生的抗体：特性及其对鸟分枝杆菌副结核亚种与巨噬细胞体外相互作用的影响
Vet Med Int. 2011;2011:258479. doi: 10.4061/2011/258479. Epub 2011 Jun 8.
5
Exposure of young dairy cattle to Mycobacterium avium subsp. paratuberculosis (MAP) through intensive grazing of contaminated pastures in a herd positive for Johne's disease.通过在患有副结核病的阳性牛群中密集放牧受污染牧场，使幼年奶牛接触鸟分枝杆菌副结核亚种（MAP）。
Can Vet J. 2010 Feb;51(2):198-200.
6
Evidence for age susceptibility of cattle to Johne's disease.牛易患约翰氏病的年龄易感性证据。
Vet J. 2010 Apr;184(1):37-44. doi: 10.1016/j.tvjl.2009.01.007. Epub 2009 Feb 25.
7
Incorporation of Mycobacterium tuberculosis lipoarabinomannan into macrophage membrane rafts is a prerequisite for the phagosomal maturation block.结核分枝杆菌脂阿拉伯甘露聚糖掺入巨噬细胞膜筏是吞噬体成熟阻滞的前提条件。
Infect Immun. 2008 Jul;76(7):2882-7. doi: 10.1128/IAI.01549-07. Epub 2008 Apr 21.
8
Bovine IgG1 antibodies against Mycobacterium avium subsp. paratuberculosis protein p34-cx improve association of bacteria and macrophages.针对副结核分枝杆菌蛋白p34-cx的牛IgG1抗体可改善细菌与巨噬细胞的结合。
Vet Res. 2008 Jan-Feb;39(1):6. doi: 10.1051/vetres:2007043. Epub 2007 Nov 9.
9
Experimental challenge models for Johne's disease: a review and proposed international guidelines.约内氏病的实验性攻毒模型：综述与国际指南建议
Vet Microbiol. 2007 Jun 21;122(3-4):197-222. doi: 10.1016/j.vetmic.2007.03.009. Epub 2007 Mar 27.
10
Application of different methods for the diagnosis of experimental paratuberculosis in goats.不同方法在山羊实验性副结核病诊断中的应用
Zoonoses Public Health. 2007;54(3-4):140-6. doi: 10.1111/j.1863-2378.2007.01006.x.