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腹腔镜可调节胃束带术和腹腔镜Roux-en-Y胃旁路术中的食管裂孔疝修补术:一项全国性数据库分析

Hiatal hernia repair in laparoscopic adjustable gastric banding and laparoscopic Roux-en-Y gastric bypass: a national database analysis.

作者信息

al-Haddad Benjamin J S, Dorman Robert B, Rasmus Nikolaus F, Kim Yong Y, Ikramuddin Sayeed, Leslie Daniel B

机构信息

Department of Surgery, 420 Delaware St. SE, MMC 290, Minneapolis, MN, 55455, USA.

出版信息

Obes Surg. 2014 Mar;24(3):377-84. doi: 10.1007/s11695-013-1106-9.

Abstract

Hiatal hernia (HH) repairs are commonly done concomitantly with laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic adjustable gastric banding (LAGB) to decrease gastroesophageal reflux disease (GERD). There is limited evidence about the additional surgical risk these combined procedures engender. We used the United States Nationwide Inpatient Sample 2004-2009 to compare mortality risk, prolonged length of stay (PLOS), and perioperative adverse events using propensity score-matched analysis. We repeated the analysis after removing patients diagnosed with GERD. There were 42,272 weighted patients undergoing LRYGB alone representing 206,559 discharges nationally and an additional 1,945 and 9,060, respectively, undergoing LRYGB + HH repair. For LAGB, there were 10,558 records representing 52,901 LAGB-only discharges and 1,959 representing 9,893 LAGB + HH repair discharges. Thirty-eight percent (95 % CI: 36, 41 %) of the patients in the LRYGB-only group had GERD compared to 55 % (51, 59 %) in the LRYGB + HH repair group. Among the LAGB groups, 31 % (28, 34 %) of LAGB-only patients had GERD compared to 44 % (38, 49 %) in the LAGB + HH repair group. We find that the average treatment effect on the treated (considering the concomitant procedure as treatment and the single procedure as control) for PLOS was -0.12353 (-0.15909, -0.08797) between the LRYGB groups and -0.04353 (-0.07488, -0.01217) for the LAGB groups. We find no evidence of increased risk of perioperative adverse events among patients undergoing concomitant HH repair with LRYGB or LAGB. Patients undergoing the combined procedure appear to be at lower risk of PLOS; this may be due to surgical training norms.

摘要

食管裂孔疝(HH)修复术通常与腹腔镜Roux-en-Y胃旁路术(LRYGB)和腹腔镜可调节胃束带术(LAGB)同时进行,以降低胃食管反流病(GERD)的发生风险。关于这些联合手术所带来的额外手术风险的证据有限。我们利用2004 - 2009年美国全国住院患者样本,采用倾向得分匹配分析来比较死亡率风险、延长住院时间(PLOS)和围手术期不良事件。在排除诊断为GERD的患者后,我们重复了该分析。单独接受LRYGB手术的加权患者有42272例,代表全国206559例出院病例,另外分别有1945例和9060例接受LRYGB + HH修复术。对于LAGB,有10558条记录代表仅LAGB手术的52901例出院病例,1959条记录代表LAGB + HH修复术的9893例出院病例。仅接受LRYGB手术的患者中38%(95% CI:36, 41%)患有GERD,而接受LRYGB + HH修复术的患者中这一比例为55%(51, 59%)。在LAGB组中,仅接受LAGB手术的患者有31%(28, 34%)患有GERD,而接受LAGB + HH修复术的患者中这一比例为44%(38, 49%)。我们发现,在LRYGB组中,PLOS的平均治疗效果(将联合手术视为治疗,单一手术视为对照)为 -0.12353(-0.15909, -0.08797),在LAGB组中为 -0.04353(-0.07488, -0.01217)。我们没有发现接受LRYGB或LAGB联合HH修复术的患者围手术期不良事件风险增加的证据。接受联合手术的患者似乎PLOS风险较低;这可能归因于手术培训规范。

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