Mortazavi Mojgan, Vahdatpour Babak, Ghasempour Aida, Taheri Diana, Shahidi Shahrzad, Moeinzadeh Firouzeh, Dolatkhah Bahareh, Dolatkhah Shahaboddin
Isfahan Kidney Disease Research Center, Department of Nephrology, Isfahan University of Medical Sciences, Isfahan, Iran.
ScientificWorldJournal. 2013 Nov 6;2013:628142. doi: 10.1155/2013/628142. eCollection 2013.
Restless leg syndrome (RLS) is one of the prevalent complaints of patients with end stage renal diseases suffering chronic hemodialysis. Although there are some known pharmacological managements for this syndrome, the adverse effect of drugs causes a limitation for using them. In this randomized clinical trial we aimed to find a nonpharmacological way to improve signs of restless leg syndrome and patients' quality of life.
Twenty-six patients were included in the study and divided into 2 groups of control and exercise. The exercise group used aerobic exercise during their hemodialysis for 16 weeks. The quality of life and severity of restless leg syndrome were assessed at the first week of study and final week. Data were analyzed using SPSS software.
The difference of means of RLS signs at the first week of study and final week was -5.5 ± 4.96 in exercise group and -0.53 ± 2.3 in control group. There was not any statistical difference between control group and exercise group in quality of life at the first week of study and final week.
We suggest using aerobic exercise for improving signs of restless leg syndrome, but no evidence was found for its efficacy on patient's quality of life.
不宁腿综合征(RLS)是终末期肾病慢性血液透析患者的常见主诉之一。尽管针对该综合征有一些已知的药物治疗方法,但药物的不良反应限制了其使用。在这项随机临床试验中,我们旨在寻找一种非药物方法来改善不宁腿综合征的症状和患者的生活质量。
26名患者纳入研究并分为对照组和运动组。运动组在血液透析期间进行有氧运动,为期16周。在研究的第一周和最后一周评估生活质量和不宁腿综合征的严重程度。使用SPSS软件分析数据。
运动组研究第一周和最后一周RLS症状的均值差异为-5.5±4.96,对照组为-0.53±2.3。研究第一周和最后一周,对照组和运动组在生活质量方面无统计学差异。
我们建议使用有氧运动改善不宁腿综合征的症状,但未发现其对患者生活质量有疗效的证据。