Rugg-Gunn Andrew, Bánóczy Jolán
School of Dental Sciences, Newcastle University, UK.
Acta Med Acad. 2013 Nov;42(2):168-78. doi: 10.5644/ama2006-124.84.
To provide a brief commentary review of fluoride-containing toothpastes and mouthrinses with emphasis on their use at home. Toothpastes and mouthrinses are just two of many ways of providing fluoride for the prevention of dental caries. The first investigations into incorporating fluoride into toothpastes and mouthrinses were reported in the middle 1940s. Unlike water fluoridation (which is 'automatic fluoridation'), fluoride-containing toothpastes and fluoridecontaining mouthrinses are, primarily, for home use and need to be purchased by the individual. By the 1960s, research indicated that fluoride could be successfully incorporated into toothpastes and clinical trials demonstrated their effectiveness. By the end of the 1970s, almost all toothpastes contained fluoride. The widespread use of fluoride- containing toothpastes is thought to be the main reason for much improved oral health in many countries. Of the many fluoride compounds investigated, sodium fluoride, with a compatible abrasive, is the most popular, although amine fluorides are used widely in Europe. The situation is similar for mouthrinses. Concentrations of fluoride (F), commonly found, are 1500 ppm (1500 μg F/g) for toothpastes and 225 ppm (225 μg F/ml) for mouthrinse. Several systematic reviews have concluded that fluoride-containing toothpastes and mouthrinses are effective, and that there is added benefit from their use with other fluoride delivery methods such as water fluoridation. Guidelines for the appropriate use of fluoride toothpastes and mouthrinses are available in many countries.
Fluoride toothpastes and mouthrinses have been developed and extensive testing has demonstrated that they are effective and their use should be encouraged.
对含氟牙膏和漱口水进行简要的评论性综述,重点关注其在家中的使用情况。牙膏和漱口水只是预防龋齿提供氟化物的众多方式中的两种。20世纪40年代中期报道了将氟化物纳入牙膏和漱口水的首批研究。与水氟化(即“自动氟化”)不同,含氟牙膏和含氟漱口水主要供家庭使用,需要个人购买。到20世纪60年代,研究表明氟化物可成功纳入牙膏,临床试验证明了它们的有效性。到20世纪70年代末,几乎所有牙膏都含有氟化物。含氟牙膏的广泛使用被认为是许多国家口腔健康大幅改善的主要原因。在研究的众多氟化物化合物中,含兼容磨料的氟化钠最受欢迎,不过胺氟化物在欧洲广泛使用。漱口水的情况类似。牙膏中常见的氟(F)浓度为1500 ppm(1500μg F/g),漱口水为225 ppm(225μg F/ml)。多项系统评价得出结论,含氟牙膏和漱口水是有效的,并且与其他氟化物输送方法(如水氟化)一起使用还有额外益处。许多国家都有关于正确使用含氟牙膏和漱口水的指南。
含氟牙膏和漱口水已研发出来,广泛的测试表明它们是有效的,应鼓励使用。