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关于 Qi 等人的评论:对头颈部放射生物学参数的估计及其临床意义。癌症,2012,4,566-580.

A Comment on Qi et al.: An Estimation of Radiobiological Parameters for Head-and-Neck and the Clinical Implications. Cancers, 2012, 4, 566-580.

机构信息

Emeritus of Departments of Human Oncology and Medical Physics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.

出版信息

Cancers (Basel). 2012 Nov 22;4(4):1225-8. doi: 10.3390/cancers4041225.

DOI:10.3390/cancers4041225
PMID:24310357
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3722597/
Abstract

Important results were shown as cell survival points in the two panels of the figure which is reproduced in this Comment letter. A curve was fitted assuming the mono-exponential recovery half-time of 17 ± 21 minutes. The wide error limits indicate that this fit is not very good, but the notable feature of both panels is that the last four points are clearly continuing to rise, above the "fitted" curve. This indicates that there is a second, slower, component of repair or recovery and this Comment explores constructively the implications of that additional discovery.

摘要

图中两个面板显示了重要的结果,以细胞存活率表示。该图在本评论信中重现。曲线拟合假设单指数恢复半衰期为 17 ± 21 分钟。宽误差范围表明这种拟合不是很好,但两个面板的显著特征是最后四点显然仍在继续上升,高于“拟合”曲线。这表明存在第二个较慢的修复或恢复成分,本评论建设性地探讨了这一额外发现的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/206d/3722597/e447672a471c/cancers-04-01225-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/206d/3722597/e447672a471c/cancers-04-01225-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/206d/3722597/e447672a471c/cancers-04-01225-g001.jpg

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本文引用的文献

1
An Estimation of Radiobiological Parameters for Head-and-Neck Cancer Cells and the Clinical Implications.头颈部癌症细胞的放射生物学参数评估及其临床意义。
Cancers (Basel). 2012 Jun 15;4(2):566-80. doi: 10.3390/cancers4020566.
2
Reports of unexpected late side effects of accelerated partial breast irradiation--radiobiological considerations.加速部分乳腺照射意外晚期副作用的报告——放射生物学考量
Int J Radiat Oncol Biol Phys. 2010 Jul 15;77(4):969-73. doi: 10.1016/j.ijrobp.2010.01.059.
3
Dose-rate effects in external beam radiotherapy redux.
外照射放疗中的剂量率效应。
Radiother Oncol. 2010 Jun;95(3):261-8. doi: 10.1016/j.radonc.2010.03.014. Epub 2010 Apr 1.
4
Loss of biological effect in prolonged fraction delivery.长时间分次给药时生物效应的丧失。
Int J Radiat Oncol Biol Phys. 2004 May 1;59(1):242-9. doi: 10.1016/j.ijrobp.2004.01.004.
5
Repair halftimes estimated from observations of treatment-related morbidity after CHART or conventional radiotherapy in head and neck cancer.根据对头颈部癌患者进行加速超分割放疗(CHART)或传统放疗后与治疗相关的发病率观察结果估算的修复半衰期。
Radiother Oncol. 1999 Dec;53(3):219-26. doi: 10.1016/s0167-8140(99)00151-6.
6
Repair capacity and kinetics of human skin during fractionated radiotherapy: erythema, desquamation, and telangiectasia after 3 and 5 year's follow-up.分割放疗期间人体皮肤的修复能力和动力学:3年和5年随访后的红斑、脱屑和毛细血管扩张
Radiother Oncol. 1989 Jun;15(2):169-88. doi: 10.1016/0167-8140(89)90131-x.