再次探讨红脸：特应性皮炎和脂溢性皮炎形式的内源性皮炎。

Red face revisited: Endogenous dermatitis in the form of atopic dermatitis and seborrheic dermatitis.

机构信息

Sector of Dermatology and Post-Graduation Course in Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rua Dona Mariana 143 / C-32 22280-020, Rio de Janeiro, Brazil.

出版信息

Clin Dermatol. 2014 Jan-Feb;32(1):109-15. doi: 10.1016/j.clindermatol.2013.05.032.

DOI:10.1016/j.clindermatol.2013.05.032

PMID:24314384

Abstract

Atopic dermatitis and seborrheic dermatitis are multifactorial dermatitides that are known collectively as endogenous dermatitis. Both conditions can affect the face, but they have clinical, epidemiological, and physiopathological peculiarities that distinguish them from each other. These two diseases are very common all around the world. Atopic dermatitis is associated with xerosis and increased susceptibility to irritants and proteins; patients with this condition have a tendency to develop asthma, allergic rhinitis, and systemic manifestations that are mediated by immunoglobulin E. Seborrheic dermatitis is a moderate chronic dermatitis that is restricted to regions with a high production of sebum and areas that have cutaneous folds. There are many studies about pathophysiology related to the immunology and genetics of atopic dermatitis, but little is known about the genetic and immunological markers of seborrheic dermatitis.

摘要

特应性皮炎和脂溢性皮炎是两种多因素的皮炎，统称为内源性皮炎。这两种疾病都可能影响面部，但它们在临床、流行病学和病理生理学方面有一些特点，可以将它们彼此区分开来。这两种疾病在全世界都非常常见。特应性皮炎与干燥和对刺激物和蛋白质的敏感性增加有关；患有这种疾病的患者有发展为哮喘、过敏性鼻炎和由免疫球蛋白 E 介导的全身表现的倾向。脂溢性皮炎是一种中度慢性皮炎，仅限于皮脂分泌旺盛的区域和有皮肤褶皱的区域。有许多关于特应性皮炎的免疫学和遗传学相关的病理生理学研究，但对脂溢性皮炎的遗传和免疫学标志物知之甚少。