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健康志愿者在自动视野检查中模拟神经科领域缺陷的能力。

The ability of healthy volunteers to simulate a neurologic field defect on automated perimetry.

机构信息

Department of Ophthalmology, University of Kentucky College of Medicine, Lexington, Kentucky.

Department of Ophthalmology, University of Kentucky College of Medicine, Lexington, Kentucky; Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky.

出版信息

Ophthalmology. 2014 Mar;121(3):759-62. doi: 10.1016/j.ophtha.2013.10.024. Epub 2013 Dec 4.

DOI:10.1016/j.ophtha.2013.10.024
PMID:24314835
Abstract

OBJECTIVE

To determine if volunteers can simulate and reproduce 3 types of neurologic field defects: hemianopia, quadrantanopia, and central scotoma.

DESIGN

Cross-sectional study.

PARTICIPANTS

Thirty healthy volunteers new to perimetry (including automated perimetry).

METHODS

After informed consent, volunteers were randomized to 1 of the 3 visual field defects listed above. All visual field testing was performed on the right eye using the Humphrey Field Analyzer (HFA; Carl Zeiss Meditec, Dublin, CA) SITA Fast 24-2 protocol. Each volunteer was provided with standard new patient instructions and was shown a diagram of the defect to be simulated. Two sets of visual fields were performed on the right eye with 10 minutes between tests. Three experts used the Ocular Hypertension Treatment Study reading center criteria and determined if the simulation was successful.

MAIN OUTCOME MEASURES

Proportion of volunteers able to simulate the assigned visual field.

RESULTS

All 10 volunteers (100%) successfully simulated a hemianopia on the first and second fields. All 10 volunteers (100%) simulated a quadrantanopia on the first field and 9 (90%) did so on the second field. Eight volunteers (80%) successfully simulated a central scotoma in the first field and all 10 (100%) did so on in the second field. Reliability criteria were excellent. Forty-seven fields (78%) had 0 fixation losses, 48 (80%) had 0 false-positive results, and 44 (73%) had 0 false-negative results.

CONCLUSIONS

It is easy to simulate reproducible and reliable neurologic field defects on automated perimetry using HFA.

摘要

目的

确定志愿者是否能够模拟和再现 3 种类型的神经视野缺陷:偏盲、象限盲和中心暗点。

设计

横断面研究。

参与者

30 名新接触视野检查(包括自动视野检查)的健康志愿者。

方法

在获得知情同意后,志愿者被随机分配到上述 3 种视觉缺陷中的 1 种。所有视野测试均在右眼使用 Humphrey 视野分析仪(HFA;Carl Zeiss Meditec,Dublin,CA)SITA Fast 24-2 方案进行。每位志愿者都接受了标准的新患者说明,并展示了要模拟的缺陷图。右眼进行了两组视野检查,两次检查之间间隔 10 分钟。三位专家使用眼高压治疗研究阅读中心标准来确定模拟是否成功。

主要观察指标

能够模拟指定视野的志愿者比例。

结果

所有 10 名志愿者(100%)在第一次和第二次视野检查中均成功模拟了偏盲。所有 10 名志愿者(100%)在第一次视野检查中模拟了象限盲,9 名(90%)在第二次视野检查中模拟了象限盲。8 名志愿者(80%)在第一次视野检查中成功模拟了中心暗点,所有 10 名志愿者(100%)在第二次视野检查中均模拟了中心暗点。可靠性标准非常优秀。47 个视野(78%)无 0 个固视丢失,48 个视野(80%)无 0 个假阳性结果,44 个视野(73%)无 0 个假阴性结果。

结论

使用 HFA 进行自动视野检查,模拟可重复且可靠的神经视野缺陷非常容易。

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