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居住在西班牙东南部的爱尔兰公民与异种移植

Irish citizens resident in the southeast of Spain and xenotransplantation.

作者信息

Ríos A, Martínez-Alarcón L, López-Navas A, Febrero B, Sánchez J, Ramis G, Ramírez P, Parrilla P

机构信息

International Collaborative Donor Project, University of Murcia, Murcia, Spain; Transplant Unit, General Surgery, Virgen de la Arrixaca Universitary Hospital, University of Murcia, Murcia, Spain; Regional Transplant Center. Consejería de Sanidad y Consumo de la Región de Murcia, University of Murcia, Murcia, Spain; Department of Surgery, University of Murcia, Murcia, Spain.

出版信息

Transplant Proc. 2013;45(10):3582-5. doi: 10.1016/j.transproceed.2013.11.001.

DOI:10.1016/j.transproceed.2013.11.001
PMID:24314965
Abstract

BACKGROUND

It is fundamental to find out the level of social acceptance of xenotransplantation (XT), especially in areas where there are preclinical projects. In the native population in the southeast of Spain this situation is well known, but in recent years there has been a considerable social change due to large migratory flows, especially concerning Ireland. The aim of this study was to analyze the attitude toward XT among the population in the southeast of Spain born in Ireland and to determine the variables affecting this attitude.

METHODS

Within the "International Collaborative Donor Project," a random sample was taken (n = 325) of the population from the southeast of Spain born in Ireland. Attitude was evaluated using a validated questionnaire, which was self-administered and completed anonymously.

RESULTS

The questionnaire completion rate was 82% (266 respondents of the 325 selected). Regarding animal organ donation for humans, if the results were similar to those achieved using human donors, 62% (n = 165) would be in favor, 30% (n = 79) undecided, and the remaining 8% (n = 22) against. If the results were worse than those achieved using human donors, 20% (n = 50) would be in favor, 59% (n = 150) undecided, and the remaining 21% (n = 54) against. Attitude toward XT is related to religion (P = .003), knowing the favorable attitude of one's religion toward transplantation (P = .037), having spoken about donation and transplantation within the family (P = .001), a partner's favorable attitude toward transplantation (P = .001), and a favorable attitude toward both deceased (P = .001) and living (P = .023) human donation.

CONCLUSIONS

Attitude toward XT among Irish citizens who are resident in the southeast of Spain is worse than that of the native Spanish population and is mainly determined by factors related to prior attitude toward the different types of human organ donation, family attitude, and religious motives.

摘要

背景

了解异种移植(XT)的社会接受程度至关重要,尤其是在有临床前项目的地区。在西班牙东南部的本地人群中,这种情况是众所周知的,但近年来,由于大量移民潮,尤其是来自爱尔兰的移民,社会发生了相当大的变化。本研究的目的是分析西班牙东南部出生于爱尔兰的人群对异种移植的态度,并确定影响这种态度的变量。

方法

在“国际合作捐赠项目”中,从西班牙东南部出生于爱尔兰的人群中随机抽取了一个样本(n = 325)。使用经过验证的问卷对态度进行评估,问卷由受访者自行填写并匿名完成。

结果

问卷完成率为82%(325名选定受访者中有266人回复)。关于动物器官用于人类移植,如果结果与使用人类供体相似,62%(n = 165)的人会表示赞成,30%(n = 79)的人不确定,其余8%(n = 22)的人反对。如果结果比使用人类供体更差,20%(n = 50)的人会表示赞成,59%(n = 150)的人不确定,其余21%(n = 会54)反对。对异种移植的态度与宗教信仰(P = .003)、了解自己宗教对移植的支持态度(P = .037)、在家庭内部谈论过捐赠和移植(P = .001)、伴侣对移植的支持态度(P = .001)以及对已故(P = .001)和活体(P = .023)人类捐赠的支持态度有关。

结论

居住在西班牙东南部的爱尔兰公民对异种移植的态度比西班牙本地人群更消极,主要由与对不同类型人类器官捐赠的先前态度、家庭态度和宗教动机相关的因素决定。

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