Auslander Beth A, Catallozzi Marina, Davis Gray, Succop Paul A, Stanberry Lawrence R, Rosenthal Susan L
Department of Pediatrics and Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX.
Department of Pediatrics, Columbia University Medical Center - College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY; Department of Population and Family Health, Columbia University Medical Center-Mailman School of Public Health and New York-Presbyterian Morgan Stanley Children's Hospital, New York, NY.
J Pediatr Adolesc Gynecol. 2014 Feb;27(1):37-40. doi: 10.1016/j.jpag.2013.08.013. Epub 2013 Dec 4.
Genital herpes, which can be spread through oral sex, is an important target for microbicides. We examined episode-specific predictors of young women's receptive oral sex and of microbicide surrogate use.
Longitudinal study.
Participants were recruited to participate in a microbicide acceptability study from adolescent clinics and local colleges and through snowballing.
Young women (ages 14 to 21 y) who reported sexual contact on at least 1 weekly phone interview (n = 181) were included from the larger sample of 208 young women.
On weekly diary phone interviews, participants reported whether or not their last sexual contact included receptive oral sex and whether or not their last sexual contact included use of a microbicide surrogate.
Participants reported a total of 1042 episodes of sexual contact of which 311 included receptive oral sex and 354 included microbicide surrogate use. Being older, having sex for the first time with a partner, and having given oral sex were associated with having received oral sex during a sexual episode. Being older, being African American, and having discussed the microbicide surrogate with their partner were associated with having used the microbicide surrogate use during a sexual episode. These results indicate that oral sex should be considered in the design of clinical trials. Future studies need to evaluate ways to promote consistent microbicide use in the context of receiving oral sex as well as those factors (eg, taste, pleasure) which may serve as a barrier.
生殖器疱疹可通过口交传播，是杀微生物剂的重要作用对象。我们研究了年轻女性接受口交及使用杀微生物剂替代物的特定事件预测因素。
纵向研究。
参与者通过青少年诊所、当地大学招募以及滚雪球式招募，参与一项杀微生物剂可接受性研究。
从208名年轻女性的更大样本中纳入了在至少一次每周电话访谈中报告有性接触的年轻女性（14至21岁，n = 181）。
在每周的日记式电话访谈中，参与者报告其上次性接触是否包括接受口交以及上次性接触是否包括使用杀微生物剂替代物。
参与者共报告了1042次性接触事件，其中311次包括接受口交，354次包括使用杀微生物剂替代物。年龄较大、首次与伴侣发生性行为以及进行过口交与在一次性接触中接受口交相关。年龄较大、非裔美国人以及与伴侣讨论过杀微生物剂替代物与在一次性接触中使用杀微生物剂替代物相关。这些结果表明，在临床试验设计中应考虑口交因素。未来研究需要评估在接受口交的情况下促进持续使用杀微生物剂的方法以及可能成为障碍的因素（如味道、快感）。
