Post-translational modifications of the histone variant H2AZ.
作者信息
Sevilla Ana, Binda Olivier
机构信息
The New York Stem Cell Foundation Laboratory, New York, NY, 10032, USA.
Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom.
出版信息
Stem Cell Res. 2014 Jan;12(1):289-95. doi: 10.1016/j.scr.2013.11.004. Epub 2013 Nov 15.
Abstract
摘要
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A histone acetylation switch regulates H2A.Z deposition by the SWR-C remodeling enzyme.一个组蛋白乙酰化开关调控 SWR-C 重塑酶的 H2A.Z 沉积。
Science. 2013 Apr 12;340(6129):195-9. doi: 10.1126/science.1229758.
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PLoS One. 2013;8(1):e54102. doi: 10.1371/journal.pone.0054102. Epub 2013 Jan 18.
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Epigenetics. 2013 Feb;8(2):177-83. doi: 10.4161/epi.23416. Epub 2013 Jan 16.
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H2A.Z facilitates access of active and repressive complexes to chromatin in embryonic stem cell self-renewal and differentiation.H2A.Z 促进活性和抑制性复合物在胚胎干细胞自我更新和分化过程中与染色质的相互作用。
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H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions.多能和多潜能干细胞中的H2A.Z景观及双重修饰构成复杂的基因组调控功能基础。
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Analysis of active chromatin modifications in early mammalian embryos reveals uncoupling of H2A.Z acetylation and H3K36 trimethylation from embryonic genome activation.早期哺乳动物胚胎中活性染色质修饰的分析表明，H2A.Z 乙酰化和 H3K36 三甲基化与胚胎基因组激活的解耦。
Epigenetics. 2012 Jul;7(7):747-57. doi: 10.4161/epi.20584. Epub 2012 Jul 1.
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