Yamatani Chihiro, Maniwa Tomohiro, Takahashi Shoji, Isaka Mitsuhiro, Ohde Yasuhisa, Endo Masahiro, Nakajima Takashi, Kondo Haruhiko
Division of Thoracic Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Gen Thorac Cardiovasc Surg. 2015 Oct;63(10):586-9. doi: 10.1007/s11748-013-0354-x. Epub 2013 Dec 7.
We herein present a case of synchronous multiple thymoma that was suspected based on the findings of positron emission tomography with fluorine-18-labeled-fluorodeoxyglucose ((18)F-FDG PET). The patient was a 70-year-old male with two similarly sized and heterogeneously enhanced masses on the right side of the anterior mediastinum on chest computed tomography. (18)F-FDG PET revealed variation in FDG accumulation between the masses, in which the maximum standardized uptake value was 4.4 in Tumor 1 and 8.7 in Tumor 2. Based on these imaging findings, the masses were suspected to be independent, likely synchronous double primary thymoma. Total thymectomy with removal of the two tumors was performed via median sternotomy. A pathological examination identified Tumor 1 as type AB thymoma and Tumor 2 as type A thymoma. This is the first reported case of synchronous multiple thymoma which was suspected based on a variation in the (18)F-FDG PET findings between the tumors.
我们在此报告一例基于氟-18标记的氟脱氧葡萄糖正电子发射断层扫描（(18)F-FDG PET）结果而怀疑为同步性多发胸腺瘤的病例。患者为一名70岁男性，胸部计算机断层扫描显示前纵隔右侧有两个大小相似且强化不均匀的肿块。(18)F-FDG PET显示两个肿块之间的FDG摄取存在差异，其中肿瘤1的最大标准化摄取值为4.4，肿瘤2为8.7。基于这些影像学表现，怀疑这些肿块是独立的，可能为同步性双原发性胸腺瘤。通过正中胸骨切开术进行了全胸腺切除术及两个肿瘤的切除。病理检查确定肿瘤1为AB型胸腺瘤，肿瘤2为A型胸腺瘤。这是首例基于肿瘤之间(18)F-FDG PET表现差异而怀疑为同步性多发胸腺瘤的报道病例。
