Grégoire Damien, Kmita Marie
Laboratory of Genetics and Development, Institut de Recherches Cliniques de Montréal (IRCM), Université de Montréal, Montréal, Québec, Canada.
Methods Mol Biol. 2014;1092:421-36. doi: 10.1007/978-1-60327-292-6_25.
Targeted cell ablation has proven to be a valuable approach to study in vivo cell functions during organogenesis, tissue homeostasis, and regeneration. Over the last two decades, various approaches have been developed to refine the control of cell ablation. In this review, we give an overview of the distinct genetic tools available for targeted cell ablation, with a particular emphasis on their respective specificity.
靶向细胞消融已被证明是一种在器官发生、组织稳态和再生过程中研究体内细胞功能的有价值方法。在过去二十年中，已开发出各种方法来优化细胞消融的控制。在本综述中，我们概述了可用于靶向细胞消融的不同遗传工具，特别强调了它们各自的特异性。
