Department of Electronic Engineering, Fudan University, Shanghai 200433, China.
Med Phys. 2013 Nov;40(11):112902. doi: 10.1118/1.4824058.
Assessment of the fetal cerebellar volume on 3D ultrasound data sets is very important in the clinical evaluation of the fetal growth and health. However, the irregular shape of the cerebellum and the strong artifacts of ultrasound images complicate the segmentation without manual intervention. In this paper, the authors propose an approach to locate the cerebellum automatically, which is considered as a prework of the segmentation.
The authors present a weighted Hough transform and a constrained randomized Hough transform to detect the fetal brain midline and the skull, respectively. By combining the location information of these two structures with local image features, a constrained probabilistic boosting tree is then proposed to search the cerebellum.
This algorithm was tested on ultrasound volumes of the fetal head with the gestational age ranging from 20 to 33 weeks. Compared with manual measurements, this algorithm obtained a satisfactory performance with the mean Dice similarity coefficient of 0.92 and the average processing time of 0.75 s per case.
The results demonstrate that the proposed method is an automatic, fast, and accurate tool for searching the fetal cerebellum on ultrasound volumes.
在三维超声数据集上评估胎儿小脑体积对于评估胎儿生长和健康状况非常重要。然而,小脑形状不规则且超声图像伪影较强,如果没有人工干预,分割工作将变得复杂。本文提出了一种自动定位小脑的方法,作为分割的前期工作。
作者提出了一种加权霍夫变换和一种约束随机霍夫变换,分别用于检测胎儿大脑中线和颅骨。然后,通过将这两个结构的位置信息与局部图像特征相结合,提出了一种约束概率提升树来搜索小脑。
该算法在 20 至 33 孕周的胎儿头部超声体积上进行了测试。与手动测量相比,该算法的平均骰子相似系数为 0.92,平均每个病例的处理时间为 0.75 秒,性能令人满意。
结果表明,该方法是一种用于在超声体积上自动、快速和准确搜索胎儿小脑的工具。