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一种草药牙膏治疗牙本质过敏症的临床疗效:一项随机对照临床试验。

Clinical efficacy of a herbal dentifrice on dentinal hypersensitivity: a randomized controlled clinical trial.

机构信息

Department of Periodontics, Government Dental College and Research Institute, Bangalore, India.

出版信息

Aust Dent J. 2013 Dec;58(4):483-90. doi: 10.1111/adj.12109.

Abstract

BACKGROUND

Dentinal hypersensitivity is a common problem and there is a growing interest in herbal based formulations for the treatment of oral diseases. This study was conducted to assess the efficacy of a commercially available novel herbal dentifrice in reduction of dentinal hypersensitivity.

METHODS

A total of 73 subjects (38 males and 35 females; aged 25-60 years) were randomly divided into two groups: Group 1 - a placebo dentifrice (The Himalaya Drug Company Research and Development, Makali, Bangalore) and Group 2 - (test group), a commercially available herbal dentifrice (Hi Ora K, The Himalaya Drug Company Research and Development, Makali, Bangalore). Sensitivity scores for controlled air stimulus and cold water were recorded at baseline, 6 weeks and 12 weeks.

RESULTS

The test group was found to be significantly better compared to the placebo group at the end of 6 and 12 weeks in reduction of dentinal hypersensitivity.

CONCLUSIONS

The novel herbal dentifrice can be recommended for treatment of dentinal hypersensitivity.

摘要

背景

牙本质过敏是一种常见的问题,人们对基于草药的口腔疾病治疗配方越来越感兴趣。本研究旨在评估一种市售新型草药牙膏在减轻牙本质过敏方面的疗效。

方法

共有 73 名受试者(38 名男性和 35 名女性;年龄 25-60 岁)被随机分为两组:第 1 组 - 安慰剂牙膏(印度喜玛拉雅药物公司研发,马加利,班加罗尔)和第 2 组 - (实验组)市售的草药牙膏(Hi Ora K,印度喜玛拉雅药物公司研发,马加利,班加罗尔)。在基线、6 周和 12 周时,记录控制空气刺激和冷水引起的敏感性评分。

结果

在第 6 周和第 12 周结束时,实验组在减轻牙本质过敏方面明显优于安慰剂组。

结论

新型草药牙膏可推荐用于治疗牙本质过敏。

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