Periodontol 2000. 2014 Feb;64(1):161-97. doi: 10.1111/j.1600-0757.2012.00458.x.
Dietary supplementation has traditionally consisted of adding vitamins and/or minerals to correct or prevent a nutritional deficiency. When supplementing the diet with other inflammatory mediators, such as essential fatty acids, there is an adjunctive benefit to the standard therapies used in the control of chronic inflammatory diseases such as Crohn's disease or rheumatoid arthritis. This review focuses on the strategies utilized for therapeutic modulation of the inflammatory cascade through dietary supplementation with specific biomolecules. Examples of how these biomolecules affect local and systemic immune responses to chronic inflammation are examined. In particular, an overview of the literature identifying the potential to modify the host response to chronic periodontitis is provided.
饮食补充传统上包括添加维生素和/或矿物质，以纠正或预防营养缺乏。当用其他炎症介质（如必需脂肪酸）补充饮食时，对于控制慢性炎症性疾病（如克罗恩病或类风湿关节炎）的标准疗法有辅助益处。本综述重点介绍了通过用特定生物分子进行饮食补充来治疗性调节炎症级联的策略。检查了这些生物分子如何影响局部和全身对慢性炎症的免疫反应的例子。特别提供了对文献的概述，确定了改变宿主对慢性牙周炎的反应的潜力。
