Discipline of Periodontics, School of Dentistry, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Periodontol 2000. 2022 Oct;90(1):146-175. doi: 10.1111/prd.12455. Epub 2022 Aug 2.
According to the new classification, periodontitis is defined as a chronic multifactorial inflammatory disease associated with dysbiotic biofilms and characterized by progressive destruction of the tooth-supporting apparatus. This definition, based on the current scientific evidence, clearly indicates and emphasizes, beside the microbial component dental biofilm, the importance of the inflammatory reaction in the progressive destruction of periodontal tissues. The idea to modulate this inflammatory reaction in order to decrease or even cease the progressive destruction was, therefore, a logical consequence. Attempts to achieve this goal involve various kinds of anti-inflammatory drugs or medications. However, there is also an increasing effort in using food supplements or so-called natural food ingredients to modulate patients' immune responses and maybe even improve the healing of periodontal tissues. The aim of this chapter of Periodontology 2000 is to review the evidence of various food supplements and ingredients regarding their possible effects on periodontal inflammation and wound healing. This review may help researchers and clinicians to evaluate the current evidence and to stimulate further research in this area.
根据新的分类，牙周炎被定义为一种与生态失调生物膜相关的慢性多因素炎症性疾病，其特征是牙齿支持组织的进行性破坏。这个定义基于当前的科学证据，除了微生物组成的牙菌斑外，还明确指出并强调了炎症反应在牙周组织进行性破坏中的重要性。因此，调节这种炎症反应以减少甚至停止进行性破坏的想法是合乎逻辑的结果。为了实现这一目标，人们尝试使用各种类型的抗炎药物或药物。然而，人们也越来越努力地使用食品补充剂或所谓的天然食品成分来调节患者的免疫反应，甚至可能改善牙周组织的愈合。《牙周病学 2000》的这一章旨在回顾各种食品补充剂和成分的证据，了解它们对牙周炎和伤口愈合的可能影响。这一综述可以帮助研究人员和临床医生评估当前的证据，并激发这一领域的进一步研究。
