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自主细小病毒之间的抗原关系。

Antigenic relationships among autonomous parvoviruses.

作者信息

Mengeling W L, Paul P S, Bunn T O, Ridpath J F

出版信息

J Gen Virol. 1986 Dec;67 ( Pt 12):2839-44. doi: 10.1099/0022-1317-67-12-2839.

DOI:10.1099/0022-1317-67-12-2839
PMID:2432167
Abstract

The antigenic relatedness of minute virus of mice (MVM), Kilham rat virus (KR), H-1 virus (H-1), haemorrhagic encephalopathy of rats virus (HER), porcine parvovirus (PPV), canine parvovirus (CPV), feline panleukopenia virus (FPV), goose parvovirus (GPV) and bovine parvovirus (BPV) was studied by immunofluorescence microscopy (FA) and by serum neutralization (SN). An antigenically related group comprising MVM, KR, HER, PPV, CPV and FPV was recognized by FA and most reactions within the group were reciprocal. Antigenic relatedness was less evident when the same viruses and antisera were tested by SN. Only CPV and FPV were closely and reciprocally related. Other cross-reactions by SN were quantitatively minor and included neutralization of CPV and FPV by pig anti-PPV serum and neutralization of H-1 and HER by rat anti-KR serum. Neither FA nor SN revealed any antigenic relationship of BPV and GPV either with each other or with any of the other viruses tested.

摘要

通过免疫荧光显微镜检查(FA)和血清中和试验(SN)研究了小鼠微小病毒(MVM)、基哈姆大鼠病毒(KR)、H - 1病毒(H - 1)、大鼠出血性脑病病毒(HER)、猪细小病毒(PPV)、犬细小病毒(CPV)、猫泛白细胞减少症病毒(FPV)、鹅细小病毒(GPV)和牛细小病毒(BPV)的抗原相关性。通过FA识别出一个由MVM、KR、HER、PPV、CPV和FPV组成的抗原相关组,该组内的大多数反应是相互的。当用SN检测相同的病毒和抗血清时,抗原相关性不太明显。只有CPV和FPV密切且相互相关。SN的其他交叉反应在数量上较少,包括猪抗PPV血清对CPV和FPV的中和作用以及大鼠抗KR血清对H - 1和HER的中和作用。FA和SN均未揭示BPV和GPV之间或它们与任何其他测试病毒之间存在任何抗原关系。

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