Pickard W F
J Theor Biol. 1986 Sep 7;122(1):1-6. doi: 10.1016/s0022-5193(86)80220-x.
Let the passage of type-lambda ions through a type-sigma channel be determined only by the ionic valence z lambda, by the thermal energy kT, by the ion concentrations on the out- and in- sides [S lambda]o and [S lambda]i, by the inside with-respect-to outside voltage of the channel E, by a single descriptor of channel saturation [S sigma lambda], and by a single descriptor (permeance) the ease of channel transit P sigma lambda. Then, if the channel current i sigma lambda, due to lambda-ions is ohmic about the Nernst potential, is a function of the sum ([S lambda]o + [S lambda]i) and not of [S lambda]o or [S lambda]i independently, and saturates in a Michaelis-Menten fashion, it follows that (Formula: see text) where F is the Faraday constant.
让λ型离子通过σ型通道的过程仅由离子价zλ、热能kT、通道内外的离子浓度[Sλ]o和[Sλ]i、通道相对于外部的内部电压E、通道饱和度的单一描述符[Sσλ]以及通道转运难易程度的单一描述符（通透率）Pσλ来决定。那么，如果由于λ离子引起的通道电流iσλ关于能斯特电位呈欧姆性，是总和（[Sλ]o + [Sλ]i）的函数，而不是独立地取决于[Sλ]o或[Sλ]i，并且以米氏方式饱和，那么可以得出（公式：见正文），其中F是法拉第常数。
