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学生对基因组学的看法:以蓝莓为例,从样本到序列。

Students' perspective on genomics: from sample to sequence using the case study of blueberry.

机构信息

Plants for Human Health Institute, North Carolina State University, Kannapolis NC, USA.

出版信息

Front Genet. 2013 Nov 26;4:245. doi: 10.3389/fgene.2013.00245. eCollection 2013.

Abstract

Advances in genomic sequencing technologies in the past decade have revolutionized the field of genomics, resulting in faster and less expensive sequencing. Holding back the potential for innovation, however, is a widespread lack of understanding of genomics and sequencing by the general public. In an attempt to remedy this problem, this paper presents an introduction to the fields of genomics, bioinformatics, and proteomics using the blueberry genome as a model case study of the plant genomics field. The blueberry (Vaccinium sect. Cyanococcus) is often cited as a "super food" in the media due to its nutritional benefits and global economic importance. There have been a number of related genomic publications in the past 20 years; however, a completed genome and a full analysis into the health-related pathways are still needed. As exemplified by this blueberry case study, there are opportunities for future genomic research into numerous beneficial plant species. The solid background presented in this paper provides future researchers the foundation to explore these uncharted areas.

摘要

在过去的十年中,基因组测序技术的进步彻底改变了基因组学领域,使测序变得更快、更便宜。然而,由于公众普遍缺乏对基因组学和测序的了解,这阻碍了创新的潜力。为了解决这个问题,本文使用蓝莓基因组作为植物基因组学领域的模型案例研究,介绍了基因组学、生物信息学和蛋白质组学领域。蓝莓( Vaccinium sect. Cyanococcus )由于其营养价值和全球经济重要性,经常在媒体上被称为“超级食物”。过去 20 年中有许多相关的基因组出版物;然而,仍然需要一个完整的基因组和一个完整的分析健康相关途径。正如这个蓝莓案例研究所示,未来对许多有益植物物种进行基因组研究存在机会。本文提供的坚实背景为未来的研究人员提供了探索这些未知领域的基础。

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