Raiskila Tero, Blanco Sequeiros Sanna, Kiuttu Jorma, Kauhanen Marja-Liisa, Läksy Kristian, Vainiemi Kirsi, Tuulio-Henriksson Annamari, Hakko Helinä, Joukamaa Matti, Veijola Juha
School of Health Sciences, University of Tampere, 33014 Tampere, Finland ; Department of Psychiatry, University Hospital of Oulu, Institute of Clinical Medicine, University of Oulu, P.O. Box 5000, 90014 Oulu, Finland ; Department of Psychiatry, University of Oulu, P.O. Box 5000, 90014 Oulu, Finland.
Depress Res Treat. 2013;2013:926562. doi: 10.1155/2013/926562. Epub 2013 Nov 10.
Objective. To evaluate the effect of an early vocational-orientated eclectic intervention on beck depression inventory (BDI) scores compared to treatment as usual in first ever depressive episode among employed people. Design. A randomized controlled trial comparing the rehabilitative intervention and the conventional treatment. Subjects. The subjects came from occupational health care units. Methods. Employees were sent to a rehabilitation center after being screened for depression using the BDI. They were diagnosed using the structured clinical interview for DSM-IV. The participating subjects (N = 283) were randomized into intervention and control groups. The intervention group received eclectic early depression intervention treatment (N = 134) and the control group was treated in the conventional way (N = 100). They were followed for one year. Results. The mean decrease in BDI scores within the intervention group was from 20.8 to 11.6 and within the control group from 19.3 to 10.8. BDI score decreased by 10 or more points in 64% of the participants in the intervention group and in 53% of the control group (P = 0.013). Conclusions. There was some evidence that early eclectic intervention in first ever episode depression may be more effective than conventional treatments among working age people in employment.
目的。评估早期职业导向的综合干预措施对首次抑郁发作的在职人员贝克抑郁量表（BDI）评分的影响，并与常规治疗进行比较。设计。一项比较康复干预和传统治疗的随机对照试验。研究对象。研究对象来自职业健康保健单位。方法。使用BDI对员工进行抑郁筛查后，将其送至康复中心。采用DSM-IV结构化临床访谈进行诊断。参与研究的对象（N = 283）被随机分为干预组和对照组。干预组接受综合早期抑郁干预治疗（N = 134），对照组接受常规治疗（N = 100）。对他们进行为期一年的随访。结果。干预组BDI评分的平均降幅从20.8降至11.6，对照组从19.3降至10.8。干预组64%的参与者BDI评分下降了10分或更多，对照组为53%（P = 0.013）。结论。有证据表明，对于在职的工作年龄人群，首次发作抑郁症的早期综合干预可能比传统治疗更有效。
