Chen Chang-Hua, Chen Wei Liang, Yen Hua-Cheng
Department of Neurosurgery, Changhua Christian Hospital, Changhua, Taiwan.
BMC Res Notes. 2013 Dec 11;6:529. doi: 10.1186/1756-0500-6-529.
Spondylodiscitis leads to debility, and few data exist on Candida spondylodiscitis in patients with intravenous drug use.
We present a case of Candida albicans lumbar spondylodiscitis in a patient with intravenous drug use. This patient was treated with surgical debridement and 9 months of fluconazole therapy, and the neurological deficits resolved completely. The infection did not recur clinically or radiologically during 9 months of follow-up.
Although Candida albicans lumbar spondylodiscitis is rare, Candida should be suspected as a causative pathogen in patients with intravenous drug use except for Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis. As soon as Candida albicans lumbar spondylodiscitis is suspected, magnetic resonance imaging and percutaneous biopsy should be performed. Surgical intervention combined with treatment with antifungal medications can successfully eradicate the infection and resolve the neurological deficits.
脊椎椎间盘炎会导致身体虚弱,而关于静脉吸毒患者念珠菌性脊椎椎间盘炎的数据很少。
我们报告一例静脉吸毒患者的白色念珠菌性腰椎间盘炎病例。该患者接受了手术清创和9个月的氟康唑治疗,神经功能缺损完全恢复。在9个月的随访期间,感染在临床和影像学上均未复发。
尽管白色念珠菌性腰椎间盘炎很少见,但除金黄色葡萄球菌、铜绿假单胞菌和结核分枝杆菌外,静脉吸毒患者应怀疑念珠菌为致病病原体。一旦怀疑白色念珠菌性腰椎间盘炎,应进行磁共振成像和经皮活检。手术干预联合抗真菌药物治疗可成功根除感染并恢复神经功能缺损。