Department of Women's and Children's Health, Karolinska Institute, Pediatric Neuropsychiatry Unit, Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Stockholm, Gävlegatan 22B, SE-113 30, Sweden.
BMC Psychiatry. 2013 Dec 13;13:336. doi: 10.1186/1471-244X-13-336.
Attention Deficit/Hyperactivity Disorder (ADHD) is associated with an increased risk of co-existing substance abuse. The Swedish legislation on compulsory healthcare can be applied to persons with severe substance abuse who can be treated involuntarily during a period of six months. This context enables a reliable clinical assessment of ADHD in individuals with severe substance use disorder (SUD).
In the context of compulsory care for individuals with severe SUD, male patients were assessed for ADHD, co-morbid psychiatric symptoms, psychosocial background, treatment history, and cognition. The data from the ADHD/SUD group (n = 60) was compared with data from (1) a group of individuals with severe substance abuse without known ADHD (SUD group, n = 120), as well as (2) a group with ADHD from an outpatient psychiatric clinic (ADHD/Psych group, n = 107).
Compared to the general SUD group in compulsory care, the ADHD/SUD group had already been significantly more often in compulsory care during childhood or adolescence, as well as imprisoned more often as adults. The most common preferred abused substance in the ADHD/SUD group was stimulant drugs, while alcohol and benzodiazepine abuse was more usual in the general SUD group. Compared to the ADHD/Psych group, the ADHD/SUD group reported more ADHD symptoms during childhood and performed poorer on all tests of general intellectual ability and executive functions.
The clinical characteristics of the ADHD/SUD group differed from those of both the SUD group and the ADHD/Psych group in several respects, indicating that ADHD in combination with SUD is a particularly disabling condition. The combination of severe substance abuse, poor general cognitive ability, severe psychosocial problems, including indications of antisocial behaviour, and other co-existing psychiatric conditions should be considered in treatment planning for adults with ADHD and SUD.
注意力缺陷多动障碍(ADHD)与共存物质滥用的风险增加有关。瑞典的强制性医疗立法适用于严重物质滥用的人,这些人可以在六个月的时间内被非自愿治疗。这种情况可以对严重物质使用障碍(SUD)个体进行可靠的 ADHD 临床评估。
在严重 SUD 个体的强制性护理背景下,对男性患者进行 ADHD、共病精神症状、社会心理背景、治疗史和认知评估。将 ADHD/SUD 组(n=60)的数据与(1)一组无已知 ADHD 的严重物质滥用个体(SUD 组,n=120)的数据进行比较,以及(2)一组来自门诊精神病诊所的 ADHD 个体(ADHD/Psych 组,n=107)的数据进行比较。
与强制性护理中的一般 SUD 组相比,ADHD/SUD 组在儿童或青少年时期已经更频繁地接受强制性护理,并且成年后更频繁地被监禁。ADHD/SUD 组最常滥用的物质是兴奋剂,而酒精和苯二氮䓬类药物滥用在一般 SUD 组中更为常见。与 ADHD/Psych 组相比,ADHD/SUD 组在儿童时期报告了更多的 ADHD 症状,并且在所有一般智力和执行功能测试中表现都更差。
ADHD/SUD 组的临床特征在几个方面与 SUD 组和 ADHD/Psych 组不同,这表明 ADHD 合并 SUD 是一种特别致残的情况。严重物质滥用、一般认知能力差、严重的社会心理问题,包括反社会行为的迹象,以及其他共存的精神疾病,应在 ADHD 和 SUD 成人的治疗计划中加以考虑。