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脉络膜转移瘤揭示了经顺铂和培美曲塞有效治疗的原发性肺透明细胞腺癌:一例报告。

Choroid metastases revealing primary clear cell adenocarcinoma of the lung effectively treated with cisplatin and pemetrexed: a case report.

作者信息

Chang Yueh-Shih, Yeung Ling, Chang Liang-Che, Huang Jen-Seng, Yeh Kun-Yun

机构信息

Division of Hemato-oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung & Chang Gung University, College of Medicine, 222 Maijin Road, Keelung, Taiwan.

出版信息

J Med Case Rep. 2013 Dec 11;7:267. doi: 10.1186/1752-1947-7-267.

DOI:10.1186/1752-1947-7-267
PMID:24330633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3930066/
Abstract

INTRODUCTION

The aim of the present report was to draw the attention of oncologists to the importance of prompt diagnosis of primary clear cell adenocarcinoma of the lung, which allows early initiation of treatment to maintain quality of life.

CASE PRESENTATION

A 63-year-old Chinese woman initially presented to our facility with multifocal bilateral choroid metastatic lesions that were found to originate from a primary clear cell adenocarcinoma of the lung (T2bN2M1b, stage IV). A thorough ophthalmologic evaluation, study of our patient's history, imaging studies and comprehensive immunohistochemical staining tests led to the diagnosis of this rare lung tumor.

CONCLUSIONS

Although this uncommon cancer is unfortunately already at a late stage when choroid metastases develop, systemic chemotherapy alone is sufficient to preserve vision and gain control over the disease.

摘要

引言

本报告旨在引起肿瘤学家对原发性肺透明细胞腺癌及时诊断重要性的关注,及时诊断有助于尽早开始治疗以维持生活质量。

病例介绍

一名63岁中国女性最初因多灶性双侧脉络膜转移灶前来我院就诊,这些转移灶被发现源自原发性肺透明细胞腺癌(T2bN2M1b,IV期)。通过全面的眼科评估、患者病史研究、影像学检查及综合免疫组化染色检测,确诊了这种罕见的肺部肿瘤。

结论

尽管不幸的是,当出现脉络膜转移时这种罕见癌症已处于晚期,但单纯全身化疗足以保留视力并控制疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b7/3930066/d4f0f58a4b0d/1752-1947-7-267-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b7/3930066/1453723a4c7a/1752-1947-7-267-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b7/3930066/d4f0f58a4b0d/1752-1947-7-267-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b7/3930066/1453723a4c7a/1752-1947-7-267-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b7/3930066/d4f0f58a4b0d/1752-1947-7-267-2.jpg

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本文引用的文献

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Choroidal metastasis as the sole initial presentation of metastatic lung cancer.脉络膜转移作为转移性肺癌的唯一初始表现。
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Bilateral choroidal metastases revealing an advanced non-small cell lung cancer.双侧脉络膜转移瘤提示晚期非小细胞肺癌。
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