Division of Critical Care Medicine; Department of Medicine; Cooper University Hospital; Camden, NJ USA.
Virulence. 2014 Jan 1;5(1):190-9. doi: 10.4161/viru.27409. Epub 2013 Dec 11.
Morbidity and mortality from sepsis remains unacceptably high. Large variability in clinical practice, plus the increasing awareness that certain processes of care associated with improved critical care outcomes, has led to the development of clinical practice guidelines in a variety of areas related to infection and sepsis. The Surviving Sepsis Guidelines for Management of Severe Sepsis and Septic Shock were first published in 2004, revised in 2008, and recently revised again and published in 2013. The first part of this manuscript is a summary of the 2013 guidelines with some editorial comment. The second part of the manuscript characterizes hospital based sepsis performance improvement programs and highlights the sepsis bundles from the Surviving Sepsis Campaign as a key component of such a program.
脓毒症的发病率和死亡率仍然高得令人无法接受。临床实践中的巨大差异，加上人们越来越意识到某些与改善重症监护结果相关的护理过程，导致了与感染和脓毒症相关的各种领域的临床实践指南的发展。《严重脓毒症和脓毒性休克管理的存活脓毒症指南》于 2004 年首次发表，2008 年修订，最近再次修订并于 2013 年发表。本文稿的第一部分是 2013 年指南的摘要，并附有一些社论评论。本文稿的第二部分描述了基于医院的脓毒症改善计划，并强调了来自拯救脓毒症运动的脓毒症捆绑作为该计划的关键组成部分。
