Medical Imaging Physics, Institute of Neuroscience and Medicine-4, Forschungszentrum Juelich, 52425, Juelich, Germany.
MAGMA. 2014 Feb;27(1):81-93. doi: 10.1007/s10334-013-0413-4. Epub 2013 Dec 15.
This article provides a comprehensive overview of oxygen ((17)O) magnetic resonance spectroscopy and imaging, including the advantages and challenges offered by the different methods developed thus far. The physiological role and relevance of oxygen, and its participation in aerobic metabolism, are addressed to emphasize the importance of the investigations and the efforts related to these developments. Furthermore, a number of methods employed in the determination of the cerebral metabolic rate of oxygen in neural cells will be presented, focusing primarily on methodologies enabling absolute quantification.
本文全面概述了氧（(17)O）磁共振波谱和成像，包括迄今为止开发的不同方法所提供的优势和挑战。文中探讨了氧的生理作用和相关性，以及它在有氧代谢中的参与，强调了这些研究和发展的重要性。此外，还介绍了几种用于确定神经细胞中氧的脑代谢率的方法，主要集中在能够实现绝对定量的方法上。
