Madeo Anne C, Tercyak Kenneth P, Tarini Beth A, McBride Colleen M
Social and Behavioral Research Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA,
Ann Behav Med. 2014 Jun;47(3):388-94. doi: 10.1007/s12160-013-9553-z.
Parents may pursue common disease risk information about themselves via multiplex genetic susceptibility testing (MGST) for their children.
To prospectively assess whether parents who received MGST disclosed their test results to their child, intended to change the child's health habits, or have the child tested.
Eighty parents who opted for free MGST completed an online survey about a child in their household before undergoing MGST and a follow-up telephone survey 3 months after receiving results.
Few parents (21 %) disclosed results to the child. Undergoing MGST was unrelated to intentions to change the child's health habits but did increase parental willingness to test the child. Greater willingness to test a child was associated with positive attitudes toward pediatric genetic testing and intentions to change the child's health habits.
The experience of receiving MGST had little impact on parents' perceptions or behaviors related to their minor child.
父母可能会通过对孩子进行多重基因易感性检测（MGST）来获取自身常见疾病风险信息。
前瞻性评估接受MGST的父母是否会向孩子披露检测结果、是否打算改变孩子的健康习惯或让孩子接受检测。
80名选择免费MGST的父母在接受MGST之前完成了一项关于其家中一名孩子的在线调查，并在收到结果3个月后接受了随访电话调查。
很少有父母（21%）向孩子披露结果。接受MGST与改变孩子健康习惯的意图无关，但确实增加了父母让孩子接受检测的意愿。更愿意让孩子接受检测与对儿科基因检测的积极态度以及改变孩子健康习惯的意图相关。
接受MGST的经历对父母关于其未成年子女的认知或行为影响甚微。
