Geller Ariane Silva Bastos, Alagia Roberta Ferreira Nazareth
Fundação de Dermatologia e Venereologia Alfredo da Matta, ManausAM, Brazil.
An Bras Dermatol. 2013 Nov-Dec;88(6 Suppl 1):193-6. doi: 10.1590/abd1806-4841.20132500.
Acne fulminans is a rare and severe form of acne that may evolve from acne vulgaris, especially in male adolescents, or occur as an adverse effect of oral isotretinoin. Arthritis is a serious clinical manifestation when the musculoskeletal system is compromised by AF and has been reported as a rare adverse effect of isotretinoin. Involvement of the sacroiliac joints occurs in 21% of acne fulminans cases. We present the case of a 18-year-old male patient in whom acne fulminans evolved from acne vulgaris grade IV and after inflammation resolution started treatment with oral isotretinoin. Within a 30-day period of retinoid treatment he presented with back pain followed by rapid, progressive inability to deambulate.
暴发性痤疮是一种罕见且严重的痤疮形式,可能由寻常痤疮演变而来,尤其在男性青少年中,或作为口服异维A酸的不良反应出现。当骨骼肌肉系统受到暴发性痤疮影响时,关节炎是一种严重的临床表现,并且已被报道为异维A酸的罕见不良反应。21%的暴发性痤疮病例会出现骶髂关节受累。我们报告一例18岁男性患者,其暴发性痤疮由IV级寻常痤疮演变而来,炎症消退后开始口服异维A酸治疗。在维甲酸治疗的30天内,他出现背痛,随后迅速进展为无法行走。