完整骨的矿物比表面积和羟基取代分析。
Analyses of mineral specific surface area and hydroxyl substitution for intact bone.
作者信息
Taylor Amanda J, Rendina Elizabeth, Smith Brenda J, Zhou Donghua H
机构信息
Department of Physics, Oklahoma State University, Stillwater, OK, USA 74078.
Department of Nutritional Sciences, Oklahoma State University, Stillwater, OK, USA 74078.
出版信息
Chem Phys Lett. 2013 Nov 19;588. doi: 10.1016/j.cplett.2013.09.061.
Abstract
Bone minerals possess two primary hydrogen sources: hydroxide ions in the nanocrystalline core and structural water in the amorphous surface layer. In order to accurately measure their concentrations using hydrogen to phosphorus cross polarization NMR spectroscopy, it is necessary to analyze the dependence of signal intensities on serial contact times, namely, cross polarization kinetics. A reliable protocol is developed to iteratively decompose the severely overlapped spectra and to analyze the cross-polarization kinetics, leading to measurement of hydroxyl and structural water concentrations. Structural water concentration is used to estimate mineral specific surface area and nanocrystal thickness for intact bone.
摘要
骨矿物质有两个主要的氢源
纳米晶核心中的氢氧根离子和无定形表面层中的结构水。为了使用氢磷交叉极化核磁共振光谱准确测量它们的浓度，有必要分析信号强度对连续接触时间的依赖性，即交叉极化动力学。开发了一种可靠的方案，用于迭代分解严重重叠的光谱并分析交叉极化动力学，从而测量羟基和结构水的浓度。结构水浓度用于估计完整骨骼的矿物质比表面积和纳米晶体厚度。
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