针对晚期乳腺癌患者通过苏达山克里亚和调息法对压力标志物及疼痛影响的随机对照试验
Randomized Controlled Trial in Advance Stage Breast Cancer Patients for the Effectiveness on Stress Marker and Pain through Sudarshan Kriya and Pranayam.
作者信息
Kumar Neeta, Bhatnagar Sushma, Velpandian T, Patnaik Santosh, Menon Geetha, Mehta Manju, Kashyap Komal, Singh Vishwajeet
机构信息
Indian Council of Medical Research, All India Institute of Medical Sciences, New Delhi, India.
Department of IRCH, Pain and Palliative care, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Indian J Palliat Care. 2013 Sep;19(3):180-5. doi: 10.4103/0973-1075.121537.
OBJECTIVE
The objective of this study is to examine the effect of a cognitive, behavioral stress management module of Sudarshan Kriya (SK) and P on levels of serum cortisol and pain among the women suffering from advanced stage breast cancer.
MATERIALS AND METHODS
Participants (n = 147) were screened and randomized to receive standard care (n = 69) versus standard along with SK and Pranayam (P) intervention (n = 78) imparted in one 18 hrs workshop spread during 3 days. Participants were expected to practice it at home 20 min daily as adjuvant to standard pharmacological treatment for pain.
RESULTS
There was a significant difference in blood cortisol levels after 3 months of practice of SK and P. Mean blood levels in the intervention arm were 341.2 ng/ml against 549.2 ng/ml in the control arm (P ≤ 0.002). Pain perception in comparison to control arm reduced by 3 points in SK and P arm on 0-10 verbal scale of pain.
CONCLUSION
SK and P is an effective intervention in reducing stress and pain among advance stage patients of breast cancer.
目的
本研究的目的是检验“苏达山克里亚（SK）与调息法（P）”认知行为压力管理模块对晚期乳腺癌女性血清皮质醇水平和疼痛的影响。
材料与方法
对147名参与者进行筛查并随机分组，一组接受标准护理（n = 69），另一组在为期3天、共18小时的研讨会上接受标准护理以及SK与调息法（P）干预（n = 78）。参与者需每天在家练习20分钟，作为疼痛标准药物治疗的辅助手段。
结果
练习SK与P三个月后，血液皮质醇水平存在显著差异。干预组的平均血液水平为341.2纳克/毫升，而对照组为549.2纳克/毫升（P≤0.002）。在0 - 10分的疼痛视觉模拟量表上，与对照组相比，SK与P组的疼痛感知降低了3分。
结论
SK与P是减轻晚期乳腺癌患者压力和疼痛的有效干预措施。
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