Kochupillai Vinod, Kumar Pratik, Singh Devinder, Aggarwal Dhiraj, Bhardwaj Narendra, Bhutani Manisha, Das Satya N
Department of Medical Oncology, Institute Rotary Cancer Hospital, New Delhi, 110029, India.
Ann N Y Acad Sci. 2005 Nov;1056:242-52. doi: 10.1196/annals.1352.039.
Stress, a psychophysiological process, acts through the immune-neuroendocrine axis and affects cellular processes of body and immune functions, leading to disease states including cancer. Stress is also linked to the habit of tobacco consumption and substance abuse, which in turn also leads to diseases. Sudarshan Kriya (SK) and Pranayam (P), rhythmic breathing processes, are known to reduce stress and improve immune functions. Cancer patients who had completed their standard therapy were studied. SK and P increased natural killer (NK) cells significantly (P <0.001) at 12 and 24 weeks of the practice compared to baseline. Increase in NK cells at 24 weeks was significant (P <0.05) compared to controls. There was no effect on T-cell subsets after SK and P either in the study group or among controls. SK and P helped to control the tobacco habit in 21% of individuals who were followed up to 6 months of practice. We conclude that the inexpensive and easy to learn and practice breathing processes (SK and P) in this study demonstrated an increase in NK cells and a reduction in tobacco consumption. When confirmed in large and randomized studies, this result could mean that the regular practice of SK and P might reduce the incidence and progression of cancer.
压力是一种心理生理过程,通过免疫 - 神经内分泌轴起作用,影响身体的细胞过程和免疫功能,导致包括癌症在内的疾病状态。压力还与烟草消费和药物滥用习惯有关,而这反过来也会导致疾病。苏达山克里亚(SK)和调息法(P)是有节奏的呼吸过程,已知它们能减轻压力并改善免疫功能。对完成标准治疗的癌症患者进行了研究。与基线相比,在练习12周和24周时,SK和P显著增加了自然杀伤(NK)细胞(P <0.001)。与对照组相比,24周时NK细胞的增加具有显著性(P <0.05)。在研究组或对照组中,SK和P对T细胞亚群均无影响。在随访至练习6个月的个体中,SK和P帮助21%的人控制了吸烟习惯。我们得出结论,本研究中这种廉价且易于学习和练习的呼吸过程(SK和P)显示出NK细胞增加以及烟草消费减少。如果在大型随机研究中得到证实,这一结果可能意味着定期练习SK和P可能会降低癌症的发病率和进展。