Vetvicka Vaclav, Vannucci Luca, Sima Petr
Department of Pathology, University of Louisville, Louisville, KY 40202, USA.
Department of Immunology, Institute of Microbiology, Prague, Czech Republic.
N Am J Med Sci. 2013 Oct;5(10):580-8. doi: 10.4103/1947-2714.120792.
Administration of glucans through immersion, dietary inclusion or injection has been found to enhance many types of immune responses, resistance to bacterial and viral infections and to environmental stress in many fish species. Although the efficacy of the glucan varies with types and administration, glucan used as an immunomodulatory and mostly immunostimulatory additive has been found satisfactory in eliciting immunity in commercial aquaculture. Development of more efficient administration methods will facilitate the routine and prophylactic use of glucans as natural immunostimulants of fish. Using a PubMed search, this review has an extensive literature on glucan in fish immunity.
通过浸泡、饲料添加或注射给予葡聚糖，已被发现可增强多种鱼类的多种免疫反应、对细菌和病毒感染的抵抗力以及对环境应激的耐受性。尽管葡聚糖的功效因类型和给药方式而异，但作为免疫调节和主要是免疫刺激添加剂的葡聚糖，已被发现在商业水产养殖中激发免疫力方面令人满意。开发更有效的给药方法将有助于葡聚糖作为鱼类天然免疫刺激剂的常规和预防性使用。通过PubMed搜索，本综述拥有关于鱼类免疫中葡聚糖的大量文献。
