Herbert Matthew S, Goodin Burel R, Pero Samuel T, Schmidt Jessica K, Sotolongo Adriana, Bulls Hailey W, Glover Toni L, King Christopher D, Sibille Kimberly T, Cruz-Almeida Yenisel, Staud Roland, Fessler Barri J, Bradley Laurence A, Fillingim Roger B
College of Arts and Sciences, Department of Psychology, University of Alabama at Birmingham, 1825 University Blvd., Shelby 177E, Birmingham, AL, 35294, USA,
Ann Behav Med. 2014 Aug;48(1):50-60. doi: 10.1007/s12160-013-9563-x.
Pain hypervigilance is an important aspect of the fear-avoidance model of pain that may help explain individual differences in pain sensitivity among persons with knee osteoarthritis (OA).
The purpose of this study was to examine the contribution of pain hypervigilance to clinical pain severity and experimental pain sensitivity in persons with symptomatic knee OA.
We analyzed cross-sectional data from 168 adults with symptomatic knee OA. Quantitative sensory testing was used to measure sensitivity to heat pain, pressure pain, and cold pain, as well as temporal summation of heat pain, a marker of central sensitization.
Pain hypervigilance was associated with greater clinical pain severity, as well as greater pressure pain. Pain hypervigilance was also a significant predictor of temporal summation of heat pain.
Pain hypervigilance may be an important contributor to pain reports and experimental pain sensitivity among persons with knee OA.
疼痛过度警觉是疼痛恐惧回避模型的一个重要方面，这可能有助于解释膝骨关节炎（OA）患者疼痛敏感性的个体差异。
本研究的目的是检验疼痛过度警觉对有症状膝OA患者临床疼痛严重程度和实验性疼痛敏感性的影响。
我们分析了168例有症状膝OA成年患者的横断面数据。采用定量感觉测试来测量对热痛、压痛和冷痛的敏感性，以及热痛的时间总和，这是中枢敏化的一个指标。
疼痛过度警觉与更高的临床疼痛严重程度以及更大的压痛相关。疼痛过度警觉也是热痛时间总和的一个重要预测因素。
疼痛过度警觉可能是膝OA患者疼痛报告和实验性疼痛敏感性的一个重要因素。
