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新诊断 2 型糖尿病患者微血管并发症的患病率。

Prevalence of microvascular complications in newly diagnosed patients with type 2 diabetes.

机构信息

Alia Ali, FCPS, Senior Registrar, Department of Medicine, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan.

Farrukh Iqbal, FRCP, Professor, Department of Medicine, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan.

出版信息

Pak J Med Sci. 2013 Jul;29(4):899-902. doi: 10.12669/pjms.294.3704.

Abstract

BACKGROUND & OBJECTIVE: Microvascular complications are the major outcome of type 2 Diabetes Mellitus progression, which reduce the quality of life, incur heavy economic burdens to the health care system and increase diabetic mortality. The aims of this study were to assess the prevalence of microvascular complications among newly diagnosed type 2 diabetic patients and to analyze the association between these complications and poor glycemic control.

METHODS

This cross sectional hospital based study was carried out in Diabetic Clinic of Shaikh Zayed Postgraduate Medical Institute, Lahore Pakistan. The study was conducted from November 2011 to November 2012 among newly diagnosed type 2 diabetic patients. Relevant information of all patients was recorded with the help of a proforma. They were investigated for retinopathy, nephropathy and neuropathy.

RESULTS

We have divided the patients into two groups: Group I with good glycemic control (HbA1c <6.5) and group II with poor glycemic control (HbA1c >6.5). In group II microvascular complications were 89.8%. Neuropathy, nephropathy and retinopathy were present in 68.5%, 56.2% and 31.4% respectively. These similar percentages in Group I were 50%, 0% and 31% respectively and are significantly lower.

CONCLUSION

The study showed that even in newly diagnosed type 2 diabetic patients who had poor glycemic control, frequency of microvascular complications is much higher as compared to those who had average glycemic control. Thus tight glycemic control does count even in newly diagnosed type 2 diabetics to prevent and minimize the occurrence of complications.

摘要

背景与目的

微血管并发症是 2 型糖尿病进展的主要结果,它降低了生活质量,给医疗保健系统带来了沉重的经济负担,并增加了糖尿病患者的死亡率。本研究旨在评估新诊断的 2 型糖尿病患者微血管并发症的患病率,并分析这些并发症与血糖控制不佳之间的关系。

方法

本横断面医院基础研究在巴基斯坦拉合尔的谢赫扎耶德研究生医学研究所的糖尿病诊所进行。该研究于 2011 年 11 月至 2012 年 11 月期间在新诊断的 2 型糖尿病患者中进行。所有患者的相关信息均在表格的帮助下记录下来。他们接受了视网膜病变、肾病和神经病变的检查。

结果

我们将患者分为两组:血糖控制良好组(HbA1c <6.5)和血糖控制不佳组(HbA1c >6.5)。在血糖控制不佳的组 II 中,微血管并发症为 89.8%。神经病变、肾病和视网膜病变的发生率分别为 68.5%、56.2%和 31.4%。在血糖控制良好的组 I 中,这些比例分别为 50%、0%和 31%,明显较低。

结论

本研究表明,即使在血糖控制不佳的新诊断 2 型糖尿病患者中,微血管并发症的发生率也远高于血糖控制良好的患者。因此,即使是新诊断的 2 型糖尿病患者,也需要严格控制血糖,以预防和最小化并发症的发生。

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