1 Pulmonary Section, Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota.
Ann Am Thorac Soc. 2014 Feb;11(2):192-7. doi: 10.1513/AnnalsATS.201305-134OC.
There are no published data regarding use of the STOP-BANG sleep apnea questionnaire in populations referred to Veterans Affairs (VA) sleep facilities. If a particular STOP-BANG score cutpoint had high positive predictive value in this referral population, it could reduce the need for diagnostic sleep studies.
STOP-BANG questionnaires were prospectively administered to veterans undergoing unattended sleep studies at a single VA facility. We evaluated the sensitivity, specificity, positive predictive value, and area under the receiver-operating characteristic curve (ROC AUC) of STOP-BANG scores for identifying a Respiratory Disturbance Index (RDI) greater than 15/hour. We also recalibrated the STOP-BANG score to our referral population, using logistic regression models.
Of 1,196 consecutive veterans undergoing unattended sleep studies, the mean STOP-BANG score was 5.7 ± 1.4, and 67% had an RDI greater than 15/hour. Sensitivities were excellent at lower STOP-BANG scores, but sharply decreased at scores of 6 and above. Specificity improved in a linear fashion with increasing scores. The ROC AUC was 0.66 (95% confidence interval [CI], 0.64-0.69) and recalibrated models improved the ROC AUC to 0.74 (95% CI, 0.69-0.78). The highest STOP-BANG score of 8 was present in only 7.9% of the sample and had a positive predictive value of 85% (95% CI, 76-92%).
The STOP-BANG questionnaire alone is insufficient to confirm the presence of significant sleep apnea. A maximal score of 8 did not have a high enough positive predictive value to forego confirmatory sleep testing.
目前尚无关于在退伍军人事务部(VA)睡眠机构就诊人群中使用 STOP-BANG 睡眠呼吸暂停问卷的发表数据。如果在该转诊人群中,特定的 STOP-BANG 评分切点具有较高的阳性预测值,那么它可以减少对诊断性睡眠研究的需求。
前瞻性地对在 VA 单家机构进行非监测性睡眠研究的退伍军人进行 STOP-BANG 问卷评估。我们评估了 STOP-BANG 评分对于识别呼吸紊乱指数(RDI)大于 15/h 的敏感性、特异性、阳性预测值和受试者工作特征曲线下的面积(ROC AUC)。我们还使用逻辑回归模型对 STOP-BANG 评分进行了重新校准,以适用于我们的转诊人群。
在 1196 例连续进行非监测性睡眠研究的退伍军人中,平均 STOP-BANG 评分为 5.7±1.4,有 67%的 RDI 大于 15/h。在较低的 STOP-BANG 评分时,敏感性很好,但在评分 6 及以上时则急剧下降。特异性随着评分的增加呈线性增加。ROC AUC 为 0.66(95%置信区间[CI],0.64-0.69),经过重新校准的模型可将 ROC AUC 提高至 0.74(95%CI,0.69-0.78)。评分最高的 8 分仅出现在样本中的 7.9%,阳性预测值为 85%(95%CI,76-92%)。
仅使用 STOP-BANG 问卷不足以确定是否存在显著的睡眠呼吸暂停。最高评分 8 分的阳性预测值不够高,不能免除确诊性睡眠测试。