Duarte Ricardo Luiz de Menezes, Fonseca Lorena Barbosa de Moraes, Magalhães-da-Silveira Flavio José, Silveira Erika Aparecida da, Rabahi Marcelo Fouad
. Sleep - Laboratório de Estudo dos Distúrbios do Sono, Centro Médico BarraShopping, Rio de Janeiro (RJ) Brasil.
. Instituto de Doenças do Tórax, Universidade Federal do Rio de Janeiro, Rio de Janeiro (RJ) Brasil.
J Bras Pneumol. 2017 Nov-Dec;43(6):456-463. doi: 10.1590/S1806-37562017000000139.
To validate the Portuguese-language version of the STOP-Bang (acronym for Snoring, Tiredness, Observed apnea, high blood Pressure, Body mass index, Age, Neck circumference, and Gender) questionnaire, culturally adapted for use in Brazil, as a means of screening for obstructive sleep apnea (OSA) in adults.
In this validation study, we enrolled patients ≥ 18 years of age, recruited between May of 2015 and November of 2016. All patients completed the STOP-Bang questionnaire and underwent overnight polysomnography. To evaluate the performance of the questionnaire, we used contingency tables and areas under the (receiver operating characteristic) curve (AUCs).
We included 456 patients. The mean age was 43.7 ± 12.5 years, and 291 (63.8%) of the patients were male. On the basis of the apnea-hypopnea index (AHI), we categorized OSA as mild/moderate/severe (any OSA; AHI ≥ 5 events/h), moderate/severe (AHI ≥ 15 events/h), or severe (AHI ≥ 30 events/h). The overall prevalence of OSA was 78.3%, compared with 52.0%, and 28.5% for moderate/severe and severe OSA, respectively. The most common score on the STOP-Bang questionnaire was 4 points (n = 106), followed by 3 points (n = 85) and 5 points (n = 82). An increase in the score was paralleled by a reduction in sensitivity with a corresponding increase in specificity for all AHI cut-off points. The AUCs obtained for the identification of any, moderate/severe, and severe OSA were: 0.743, 0.731, and 0.779, respectively. For any OSA, the score on the questionnaire (cut-off, ≥ 3 points) presented sensitivity, specificity, and accuracy of 83.5%, 45.5%, and 75.2%, respectively.
The STOP-Bang questionnaire performed adequately for OSA screening, indicating that it could be used as an effective screening tool for the disorder.
验证经文化调适后适用于巴西的葡萄牙语版STOP-Bang问卷(Snoring、Tiredness、Observed apnea、high blood Pressure、Body mass index、Age、Neck circumference和Gender的首字母缩写),作为成人阻塞性睡眠呼吸暂停(OSA)的筛查工具。
在这项验证研究中,我们纳入了2015年5月至2016年11月期间招募的18岁及以上患者。所有患者均完成了STOP-Bang问卷并接受了夜间多导睡眠图检查。为评估问卷的性能,我们使用了列联表和(受试者操作特征)曲线下面积(AUC)。
我们纳入了456例患者。平均年龄为43.7±12.5岁,其中291例(63.8%)为男性。根据呼吸暂停低通气指数(AHI),我们将OSA分为轻度/中度/重度(任何OSA;AHI≥5次/小时)、中度/重度(AHI≥15次/小时)或重度(AHI≥30次/小时)。OSA的总体患病率为78.3%,中度/重度和重度OSA的患病率分别为52.0%和28.5%。STOP-Bang问卷最常见的得分为4分(n=106),其次是3分(n=85)和5分(n=82)。对于所有AHI切点,得分增加的同时敏感性降低,特异性相应增加。用于识别任何OSA、中度/重度OSA和重度OSA的AUC分别为:0.743、0.731和0.779。对于任何OSA,问卷得分(切点,≥3分)的敏感性、特异性和准确性分别为83.5%、45.5%和75.2%。
STOP-Bang问卷在OSA筛查中表现良好,表明它可作为该疾病的有效筛查工具。