Merin S, Blair N P, Tso M O
Invest Ophthalmol Vis Sci. 1987 Apr;28(4):756-9.
Twenty-two phakic eyes of 16 patients with varying stages of senile macular degeneration (SMD) underwent vitreous fluorophotometry. The upper tolerance limit of the penetration ratio in 17 eyes of 17 age-matched controls was 6.33 X 10(-6) min-1. Ten of the 22 eyes with SMD had values exceeding this, indicating abnormal blood-retinal barrier function. When the fluorescence recorded in the vitreous but not related to the local intravitreal dye was evaluated, it was greater in those eyes with more severe forms of the disease. All ten eyes with drusen alone and no SMD had normal fluorophotometry values. Vitreous fluorophotometry may be helpful in the diagnosis and classification of SMD.
对16例不同阶段老年性黄斑变性（SMD）患者的22只屈光间质完整的眼睛进行了玻璃体荧光光度测定。17例年龄匹配的对照者的17只眼中，透过率的上限为6.33×10⁻⁶分钟⁻¹。22只患SMD的眼睛中有10只超过了该值，表明血视网膜屏障功能异常。当评估玻璃体中记录的与局部玻璃体内染料无关的荧光时，病情较重的眼睛中荧光更强。仅患有玻璃膜疣而无SMD的所有10只眼睛的荧光光度测定值均正常。玻璃体荧光光度测定可能有助于SMD的诊断和分类。
