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一株从美国中西部猪群中分离得到的（美国/爱荷华州/18984/2013）噬菌斑克隆的强毒猪流行性腹泻病毒的全基因组序列

Full-Length Genome Sequence of a Plaque-Cloned Virulent Porcine Epidemic Diarrhea Virus Isolate (USA/Iowa/18984/2013) from a Midwestern U.S. Swine Herd.

作者信息

Hoang Hai, Killian Mary L, Madson Darin M, Arruda Paulo H E, Sun Dong, Schwartz Kent J, Yoon Kyoungjin J

机构信息

Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.

出版信息

Genome Announc. 2013 Dec 19;1(6):e01049-13. doi: 10.1128/genomeA.01049-13.

DOI:10.1128/genomeA.01049-13
PMID:24356830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3868854/
Abstract

Porcine epidemic diarrhea (PED) was recognized in U.S. swine for the first time in early 2013. A plaque-purified PED virus (PEDV) isolate (USA/Iowa/18984/2013) was obtained from a diarrheic piglet. The isolate is genetically close to other previously reported U.S. PEDVs and recent Chinese PEDVs and was virulent when inoculated into neonatal pigs.

摘要

2013年初，猪流行性腹泻（PED）首次在美国猪群中被发现。从一头腹泻仔猪中获得了一株经蚀斑纯化的猪流行性腹泻病毒（PEDV）分离株（USA/Iowa/18984/2013）。该分离株在基因上与其他先前报道的美国PEDV以及最近的中国PEDV相近，接种新生仔猪时具有致病性。

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