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用于小儿清醒镇静的口腔雾化咪达唑仑评估。

Assessment of buccal aerosolized midazolam for pediatric conscious sedation.

作者信息

Chopra Radhika, Marwaha Mohita

机构信息

Department of Pedodontics and Preventive Dentistry, SGT Dental College and Research Institute, Gurgaon, Haryana, India.

出版信息

J Investig Clin Dent. 2015 Feb;6(1):40-4. doi: 10.1111/jicd.12062. Epub 2013 Dec 20.

Abstract

AIM

To assess the acceptance and efficacy of aerosolized midazolam through buccal mucosa for conscious sedation.

METHODS

Thirty-five children aged 2-6 years with Grade I and II Frankl behavior rating scale were selected for various dental procedures under local anesthesia. Initially behavior-shaping procedures were used and Houpt behavior scoring was recorded. Thereafter, midazolam was administered using a spray through buccal mucosa and scores for acceptance of drug and behavior after sedation were recorded. The data were compiled and a Wilcoxon signed ranks test was used to assess the difference in behavior before and after the sedation.

RESULTS

Eighty-three percent of the patients accepted the drug without any complaint. A statistically significant improvement was seen in the Houpt scores before and after drug administration (P < 0.001).

CONCLUSIONS

Buccal aerosolized midazolam can be used successfully for pediatric conscious sedation.

摘要

目的

评估雾化咪达唑仑经颊黏膜用于清醒镇静的接受度和疗效。

方法

选取35名年龄在2至6岁、Frankl行为评级量表为I级和II级的儿童,在局部麻醉下进行各种牙科手术。最初采用行为塑造程序并记录Houpt行为评分。此后,通过颊黏膜使用喷雾剂给予咪达唑仑,并记录药物接受度和镇静后行为评分。对数据进行整理,采用Wilcoxon符号秩检验评估镇静前后行为的差异。

结果

83%的患者接受药物且无任何抱怨。给药前后Houpt评分有统计学意义的改善(P < 0.001)。

结论

颊部雾化咪达唑仑可成功用于小儿清醒镇静。

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