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Can genetic information change patient behavior to reduce Type 2 diabetes risk?

作者信息

Vassy Jason L

机构信息

Section of General Internal Medicine, VA Boston HealthCare System, MA, USA, and G2P Research Program, Division of General Internal Medicine & Primary Care, Department of Medicine, Brigham & Women's Hospital, MA, USA, and Department of Medicine, Harvard Medical School, 150 South Huntington Avenue, Building 9, Suite 425, Boston, MA 02130, USA, Tel.: +1 857 364 2561, ,

出版信息

Per Med. 2013 Jan 1;10(1). doi: 10.2217/pme.12.116.

DOI:10.2217/pme.12.116
PMID:24358047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3864859/
Abstract
摘要

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本文引用的文献

1
Genotype prediction of adult type 2 diabetes from adolescence in a multiracial population.从多民族人群的青春期预测成年 2 型糖尿病的基因型。
Pediatrics. 2012 Nov;130(5):e1235-42. doi: 10.1542/peds.2012-1132. Epub 2012 Oct 15.
2
Personalized genetic risk counseling to motivate diabetes prevention: a randomized trial.个性化遗传风险咨询以促进糖尿病预防：一项随机试验。
Diabetes Care. 2013 Jan;36(1):13-9. doi: 10.2337/dc12-0884. Epub 2012 Aug 28.
3
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.大规模的关联分析为 2 型糖尿病的遗传结构和病理生理学提供了深入了解。
Nat Genet. 2012 Sep;44(9):981-90. doi: 10.1038/ng.2383. Epub 2012 Aug 12.
4
Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design.2 型糖尿病风险基因检测对健康行为和结果的影响：研究背景、方法和设计。
BMC Health Serv Res. 2012 Jan 18;12:16. doi: 10.1186/1472-6963-12-16.
5
Design of a randomized trial of diabetes genetic risk testing to motivate behavior change: the Genetic Counseling/lifestyle Change (GC/LC) Study for Diabetes Prevention.糖尿病遗传风险检测以促进行为改变的随机试验设计：预防糖尿病的遗传咨询/生活方式改变（GC/LC）研究。
Clin Trials. 2011 Oct;8(5):609-15. doi: 10.1177/1740774511414159.
6
Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program.基于 34 个已确认的 2 型糖尿病基因座的更新遗传评分与糖尿病预防计划中的糖尿病发病率和血糖正常化的逆转相关。
Diabetes. 2011 Apr;60(4):1340-8. doi: 10.2337/db10-1119. Epub 2011 Mar 4.
7
Effect of direct-to-consumer genomewide profiling to assess disease risk.直接面向消费者的全基因组分析评估疾病风险的效果。
N Engl J Med. 2011 Feb 10;364(6):524-34. doi: 10.1056/NEJMoa1011893. Epub 2011 Jan 12.
8
Identifying primary care patients at risk for future diabetes and cardiovascular disease using electronic health records.利用电子健康记录识别未来患有糖尿病和心血管疾病风险的初级保健患者。
BMC Health Serv Res. 2009 Sep 22;9:170. doi: 10.1186/1472-6963-9-170.
9
The clinical application of genetic testing in type 2 diabetes: a patient and physician survey.基因检测在 2 型糖尿病中的临床应用：患者和医生调查。
Diabetologia. 2009 Nov;52(11):2299-2305. doi: 10.1007/s00125-009-1512-7. Epub 2009 Sep 2.
10
Genotype score in addition to common risk factors for prediction of type 2 diabetes.除常见风险因素外，基因型评分对2型糖尿病的预测作用
N Engl J Med. 2008 Nov 20;359(21):2208-19. doi: 10.1056/NEJMoa0804742.