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深龋患牙牙髓的治疗——文献系统综述

Treatment of pulps in teeth affected by deep caries - A systematic review of the literature.

作者信息

Bergenholtz Gunnar, Axelsson Susanna, Davidson Thomas, Frisk Fredrik, Hakeberg Magnus, Kvist Thomas, Norlund Anders, Petersson Arne, Portenier Isabelle, Sandberg Hans, Tranæus Sofia, Mejare Ingegerd

机构信息

Varsaparken, Gothenburg, Sweden.

Varsaparken, Gothenburg, Sweden.

出版信息

Singapore Dent J. 2013 Dec;34(1):1-12. doi: 10.1016/j.sdj.2013.11.001.

Abstract

BACKGROUND

This systematic review assesses the effect of methods commonly used to manage the pulp in cases of deep caries lesions, and the extent the pulp chamber remains uninfected and does not cause pulpal or periapical inflammatory lesions and associated tooth-ache over time.

STUDY DESIGN

An electronic literature search included the databases PubMed, EMBASE, The Cochrane Central Register of Controlled Trials and Cochrane Reviews from January 1950 to March 2013. In addition, hand searches were carried out. Two reviewers independently evaluated abstracts and full-text articles. An article was read in full if at least one of the two reviewers considered the abstract potentially relevant. Altogether, 161 articles were read in full text. Of these, 24 studies fulfilled established inclusion criteria. Based on studies of at least moderate quality, the quality of evidence of each procedure was rated in four levels according to GRADE.

RESULTS

No study reached the high quality level. Twelve were of moderate quality. The overall evidence was insufficient to assess which of indirect pulp capping, stepwise excavation, direct excavation and pulp capping/partial pulpotomy, pulpotomy or pulpectomy is the most effective treatment approach for teeth with deep caries.

CONCLUSIONS

Because of the lack of good studies it is not possible to determine whether an injured pulp by deep caries can be maintained or whether it should be removed and replaced with a root canal filling. Both randomized studies and prospective observational studies are needed to investigate whether a pulp exposed to deep caries is best treated by measures intended to preserve it or by pulpectomy and root filling.

摘要

背景

本系统评价评估了深龋病变时常用的牙髓处理方法的效果,以及随着时间推移,牙髓腔未受感染、未引起牙髓或根尖周炎症病变及相关牙痛的程度。

研究设计

电子文献检索包括1950年1月至2013年3月期间的PubMed、EMBASE、Cochrane对照试验中央注册库和Cochrane系统评价数据库。此外,还进行了手工检索。两名评价员独立评估摘要和全文文章。如果两名评价员中至少有一人认为摘要可能相关,则全文阅读该文章。总共全文阅读了161篇文章。其中,24项研究符合既定的纳入标准。基于至少中等质量的研究,根据GRADE将每个程序的证据质量分为四个等级。

结果

没有研究达到高质量水平。12项为中等质量。总体证据不足以评估间接盖髓术、逐步去龋、直接去龋和盖髓术/部分牙髓切断术、牙髓切断术或牙髓摘除术哪种是治疗深龋牙齿最有效的方法。

结论

由于缺乏高质量研究,无法确定深龋损伤的牙髓能否保留,还是应予以摘除并用根管充填物替代。需要随机研究和前瞻性观察研究来调查暴露于深龋的牙髓采用保存措施还是牙髓摘除术和根管充填治疗效果更佳。

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