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人潘氏细胞中胰腺分泌蛋白的免疫组织化学证明

Immunohistochemical demonstration of pancreatic secretory proteins in human paneth cells.

作者信息

Bohe M, Lindström C, Ohlsson K

出版信息

Scand J Gastroenterol Suppl. 1986;126:65-8. doi: 10.3109/00365528609091896.

DOI:10.3109/00365528609091896
PMID:2436286
Abstract

Gastro-intestinal mucosa obtained at surgical resection was studied by light microscopy using the unlabelled antibody enzyme method for immunohistochemical staining of lysozyme, anionic trypsin, cationic trypsin and pancreatic trypsin inhibitor (PSTI). Paneth cells, identified by their content of lysozyme, contained anionic trypsin, cationic trypsin and PSTI-like immunoreactivity. The demonstration of immunoreactive trypsin and immunoreactive PSTI is a further indication of the resemblance between Paneth cells and the pancreatic acinar cells.

摘要

采用未标记抗体酶法对手术切除获取的胃肠道黏膜进行光镜研究,以对溶菌酶、阴离子胰蛋白酶、阳离子胰蛋白酶和胰腺胰蛋白酶抑制剂(PSTI)进行免疫组织化学染色。通过溶菌酶含量鉴定的潘氏细胞含有阴离子胰蛋白酶、阳离子胰蛋白酶和PSTI样免疫反应性。免疫反应性胰蛋白酶和免疫反应性PSTI的证实进一步表明了潘氏细胞与胰腺腺泡细胞之间的相似性。

相似文献

1
Immunohistochemical demonstration of pancreatic secretory proteins in human paneth cells.人潘氏细胞中胰腺分泌蛋白的免疫组织化学证明
Scand J Gastroenterol Suppl. 1986;126:65-8. doi: 10.3109/00365528609091896.
2
Pancreatic endoproteases and pancreatic secretory trypsin inhibitor immunoreactivity in human Paneth cells.人潘氏细胞中胰腺内蛋白酶和胰腺分泌性胰蛋白酶抑制剂的免疫反应性
J Clin Pathol. 1986 Jul;39(7):786-93. doi: 10.1136/jcp.39.7.786.
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Trypsin-like immunoreactivity in human Paneth cells.人类潘氏细胞中的类胰蛋白酶免疫反应性。
Digestion. 1984;30(4):271-5. doi: 10.1159/000199119.
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Varying occurrence of gastroduodenal immunoreactive pancreatic secretory trypsin inhibitor.胃十二指肠免疫反应性胰分泌性胰蛋白酶抑制剂的发生率各异。
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Immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal mucosa.
Adv Exp Med Biol. 1988;240:101-5. doi: 10.1007/978-1-4613-1057-0_12.
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Production and secretion of pancreatic secretory trypsin inhibitor in normal human small intestine.正常人体小肠中胰腺分泌性胰蛋白酶抑制剂的产生与分泌。
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Immunohistochemical localization of pancreatic secretory trypsin inhibitor in fetal and adult pancreatic and extrapancreatic tissues.胰腺分泌型胰蛋白酶抑制剂在胎儿及成人胰腺和胰腺外组织中的免疫组织化学定位
J Histochem Cytochem. 1986 Feb;34(2):227-35. doi: 10.1177/34.2.3511141.
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Immunoglobulins within human small-intestinal Paneth cells.人类小肠潘氏细胞内的免疫球蛋白。
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Distribution of pancreatic secretory trypsin inhibitor in various human tissues and its inactivation in the gastric mucosa.胰腺分泌性胰蛋白酶抑制剂在人体各组织中的分布及其在胃黏膜中的失活
Res Commun Chem Pathol Pharmacol. 1987 Feb;55(2):243-8.
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Effects of cholecystokinin and carbamylcholine on Paneth cell secretion in mice: a comparison with pancreatic acinar cells.胆囊收缩素和氨甲酰胆碱对小鼠潘氏细胞分泌的影响:与胰腺腺泡细胞的比较
Anat Rec. 1989 Oct;225(2):124-32. doi: 10.1002/ar.1092250207.

引用本文的文献

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Prognostic significance of the labeling of Adnab-9 in pancreatic intraductal papillary mucinous neoplasms.Adnab-9标记在胰腺导管内乳头状黏液性肿瘤中的预后意义
Int J Pancreatol. 2001;29(3):141-50. doi: 10.1385/IJGC:29:3:141.
2
Effect of live and heat-killed bacteria on the secretory activity of Paneth cells in germ-free mice.活细菌和热灭活细菌对无菌小鼠潘氏细胞分泌活性的影响。
Cell Tissue Res. 1988 Jan;251(1):87-93. doi: 10.1007/BF00215451.
3
Crystalloid lysozyme inclusions in Paneth cells of vitamin A-deficient rats.维生素A缺乏大鼠潘氏细胞中的晶体状溶菌酶包涵体。
Cell Tissue Res. 1990 May;260(3):625-8. doi: 10.1007/BF00297244.
4
Antibodies to a trypsin sensitive pancreatic antigen in chronic inflammatory bowel disease: specific markers for a subgroup of patients with Crohn's disease.慢性炎症性肠病中针对一种胰蛋白酶敏感胰腺抗原的抗体:克罗恩病患者亚组的特异性标志物
Gut. 1991 Oct;32(10):1192-7. doi: 10.1136/gut.32.10.1192.