• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

羊膜与富血小板纤维蛋白治疗牙龈退缩的随机对照试验

Amniotic membrane versus platelet-rich fibrin in treatment of gingival recession- a randomized control trial.

作者信息

Chaitra M P, Shankar Shrinidhi Maji, Shivakumar T P, Gururaj Soumya B, Chidambar Chethana K, Bhushan Kala S

机构信息

Department of Periodontology, Sharavathi Dental College and Hospital, Shimoga, India.

Department of Periodontology, Subbaih Institute of Dental Sciences, Shimoga, India.

出版信息

Saudi Dent J. 2024 Jan;36(1):192-197. doi: 10.1016/j.sdentj.2023.11.011. Epub 2023 Nov 17.

DOI:10.1016/j.sdentj.2023.11.011
PMID:38375378
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10874856/
Abstract

OBJECTIVE

To determine the efficacy of latelet-rich fibrin (PRF) and Amniotic membrane (AM) along with the coronally advanced flap (CAF) technique in treating Miller's class I gingival recession (GR) defects.

MATERIAL AND METHODS

A total of 32 sites with Miller's class I GR defects were distributed into Group A (CAF + PRF, n = 16) and Group B (CAF + AM, n = 16). Clinical parameters like gingival index (GI), plaque index (PI), gingival bleeding index (GBI), gingival sulcus depth (GSD), relative attachment level (RAL), and gingival marginal level (GML) were measured at baseline and at 3, 6 and 9 months after surgical intervention.

RESULTS

PRF and AM with CAF were effective treatment modalities for treating Miller's class I GR defects, with an average root coverage value of 2.00 ± 0.75 mm in Group A and 1.5 ± 0.3 mm in Group B. Complete coverage (100 %) was obtained in 57 % sites of group A and 49 % sites of group B. At the 9-month follow-up, there was a significant increase in relative attachment levels in both groups when compared to baseline.

CONCLUSION

In the present study it was observed that there was a clinically and statistically significant improvement in root coverage with both groups. PRF-treated sites showed > 50 % complete coverage and hence were superior. AM showed comparable results to PRF and could be used as an alternative.

摘要

目的

确定富血小板纤维蛋白(PRF)和羊膜(AM)联合冠向推进瓣(CAF)技术治疗米勒I类牙龈退缩(GR)缺损的疗效。

材料与方法

将32个患有米勒I类GR缺损的部位分为A组(CAF + PRF,n = 16)和B组(CAF + AM,n = 16)。在基线以及手术干预后3、6和9个月测量临床参数,如牙龈指数(GI)、菌斑指数(PI)、牙龈出血指数(GBI)、牙龈沟深度(GSD)、相对附着水平(RAL)和牙龈边缘水平(GML)。

结果

PRF和AM联合CAF是治疗米勒I类GR缺损的有效治疗方式,A组平均牙根覆盖值为2.00±0.75mm,B组为1.5±0.3mm。A组57%的部位和B组49%的部位实现了完全覆盖(100%)。在9个月的随访中,与基线相比,两组的相对附着水平均有显著增加。

结论

在本研究中观察到,两组的牙根覆盖在临床和统计学上均有显著改善。PRF治疗的部位显示>50%的完全覆盖,因此更具优势。AM显示出与PRF相当的结果,可作为替代方案使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3d9/10874856/0c745867d34a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3d9/10874856/8514d1adc95b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3d9/10874856/cbf5dee0d51f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3d9/10874856/0c745867d34a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3d9/10874856/8514d1adc95b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3d9/10874856/cbf5dee0d51f/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3d9/10874856/0c745867d34a/gr3.jpg

相似文献

1
Amniotic membrane versus platelet-rich fibrin in treatment of gingival recession- a randomized control trial.羊膜与富血小板纤维蛋白治疗牙龈退缩的随机对照试验
Saudi Dent J. 2024 Jan;36(1):192-197. doi: 10.1016/j.sdentj.2023.11.011. Epub 2023 Nov 17.
2
Patient-centered evaluation of microsurgical management of gingival recession using coronally advanced flap with platelet-rich fibrin or amnion membrane: A comparative analysis.采用富含血小板纤维蛋白或羊膜的冠向推进瓣对牙龈退缩进行以患者为中心的显微手术治疗评估:一项对比分析。
Eur J Dent. 2016 Jan-Mar;10(1):121-133. doi: 10.4103/1305-7456.175686.
3
Clinical Evaluation of Coronally Advanced Flap With or Without Advance-Platelet Rich Fibrin Membrane in the Treatment of Miller's Class-II Localized Gingival Recession: A Clinical Study.采用或不采用预富血小板纤维蛋白膜的冠向推进瓣治疗Miller II类局限性牙龈退缩的临床评估:一项临床研究
Cureus. 2023 Feb 13;15(2):e34919. doi: 10.7759/cureus.34919. eCollection 2023 Feb.
4
Comparative clinical evaluation of coronally advanced flap with or without platelet rich fibrin membrane in the treatment of isolated gingival recession.富血小板纤维蛋白膜辅助或不辅助冠向复位瓣治疗单纯性牙龈退缩的临床对比评估
J Indian Soc Periodontol. 2015 Jan-Feb;19(1):66-71. doi: 10.4103/0972-124X.145790.
5
Comparative Evaluation of Clinical Efficacy of Leukocyte-Rich Platelet-Rich Fibrin with Advanced Platelet-Rich Fibrin in Management of Gingival Recession Defects: A Randomized Controlled Trial.富白细胞富血小板纤维蛋白与先进富血小板纤维蛋白治疗牙龈退缩缺损的临床疗效比较评估:一项随机对照试验。
Med Princ Pract. 2022;31(4):376-383. doi: 10.1159/000525560. Epub 2022 Jun 21.
6
Comparative Evaluation of Coronally Advanced Flap Using Amniotic Membrane and Platelet-rich Fibrin Membrane in Gingival Recession: An 18-Month Clinical Study.使用羊膜和富血小板纤维蛋白膜的冠向推进瓣治疗牙龈退缩的比较评估:一项18个月的临床研究。
Contemp Clin Dent. 2018 Apr-Jun;9(2):188-194. doi: 10.4103/ccd.ccd_799_17.
7
Evaluation of periosteum eversion and coronally advanced flap techniques in the treatment of isolated Miller's Class I/II gingival recession: A comparative clinical study.骨膜翻瓣术与冠向推进瓣技术治疗孤立性米勒I/II类牙龈退缩的疗效评估:一项对比临床研究。
J Indian Soc Periodontol. 2018 Mar-Apr;22(2):140-149. doi: 10.4103/jisp.jisp_5_18.
8
A split mouth randomized controlled study to evaluate the adjunctive effect of platelet-rich fibrin to coronally advanced flap in Miller's class-I and II recession defects.一项评估富血小板纤维蛋白对米勒I类和II类牙龈退缩缺损的冠向推进瓣辅助作用的双侧随机对照研究。
J Indian Soc Periodontol. 2013 Sep;17(5):631-6. doi: 10.4103/0972-124X.119281.
9
Evaluation of the effect of dose-dependent platelet-rich fibrin membrane on treatment of gingival recession: a randomized, controlled clinical trial.剂量依赖性富血小板纤维蛋白膜治疗牙龈退缩效果的评估:一项随机对照临床试验。
J Appl Oral Sci. 2018 May 14;26:e20170278. doi: 10.1590/1678-7757-2017-0278.
10
Comparative evaluation of human chorion membrane and platelet-rich fibrin membrane with coronally advanced flap in treatment of Miller's class I and II recession defects: A randomized controlled study.人绒毛膜膜和富血小板纤维蛋白膜联合冠向推进瓣治疗Miller I级和II级牙龈退缩缺损的比较评估:一项随机对照研究。
J Indian Soc Periodontol. 2019 Mar-Apr;23(2):152-157. doi: 10.4103/jisp.jisp_408_18.

引用本文的文献

1
Comparative evaluation of amniotic membrane and titanium-prepared platelet-rich fibrin in root coverage: A randomized split-mouth clinical trial.羊膜与钛制备富血小板纤维蛋白用于牙根覆盖的比较评估:一项随机分口临床试验。
J Oral Biol Craniofac Res. 2025 Sep-Oct;15(5):1001-1009. doi: 10.1016/j.jobcr.2025.07.002. Epub 2025 Jul 10.

本文引用的文献

1
Patient-centered evaluation of microsurgical management of gingival recession using coronally advanced flap with platelet-rich fibrin or amnion membrane: A comparative analysis.采用富含血小板纤维蛋白或羊膜的冠向推进瓣对牙龈退缩进行以患者为中心的显微手术治疗评估:一项对比分析。
Eur J Dent. 2016 Jan-Mar;10(1):121-133. doi: 10.4103/1305-7456.175686.
2
Use of Platelet-Rich Fibrin Membrane in the Treatment of Gingival Recession: A Systematic Review and Meta-Analysis.富血小板纤维蛋白膜在牙龈退缩治疗中的应用:一项系统评价与荟萃分析。
J Periodontol. 2016 Mar;87(3):281-90. doi: 10.1902/jop.2015.150420. Epub 2015 Nov 12.
3
Amniotic membrane - A Novel material for the root coverage: A case series.
羊膜——一种用于牙根覆盖的新型材料:病例系列
J Indian Soc Periodontol. 2015 Jul-Aug;19(4):444-8. doi: 10.4103/0972-124X.154166.
4
Efficacy of Human Chorion Membrane Allograft for Recession Coverage: A Case Series.人绒毛膜同种异体移植用于退缩覆盖的疗效:病例系列
J Periodontol. 2015 Aug;86(8):941-4. doi: 10.1902/jop.2014.140025c.
5
Amnion membrane for coverage of gingival recession: A novel application.羊膜覆盖牙龈退缩:一种新应用。
Contemp Clin Dent. 2014 Jul;5(3):293-5. doi: 10.4103/0976-237X.137900.
6
Bilateral multiple recession coverage with platelet-rich fibrin in comparison with amniotic membrane.与羊膜相比,富含血小板纤维蛋白的双侧多次结膜退缩覆盖术
J Indian Soc Periodontol. 2014 Jan;18(1):102-6. doi: 10.4103/0972-124X.128261.
7
Comparison of amnion allograft with connective tissue graft for root coverage procedures: a double-blind, randomized, controlled clinical trial.羊膜同种异体移植与结缔组织移植用于牙根覆盖手术的比较:一项双盲、随机、对照临床试验。
J Int Acad Periodontol. 2013 Oct;15(4):101-12.
8
A split mouth randomized controlled study to evaluate the adjunctive effect of platelet-rich fibrin to coronally advanced flap in Miller's class-I and II recession defects.一项评估富血小板纤维蛋白对米勒I类和II类牙龈退缩缺损的冠向推进瓣辅助作用的双侧随机对照研究。
J Indian Soc Periodontol. 2013 Sep;17(5):631-6. doi: 10.4103/0972-124X.119281.
9
Development of tissue bank.组织库的发展
Indian J Plast Surg. 2012 May;45(2):396-402. doi: 10.4103/0970-0358.101326.
10
Use of platelet-rich fibrin membrane following treatment of gingival recession: a randomized clinical trial.富血小板纤维蛋白膜用于牙龈退缩治疗后的效果:一项随机临床试验
Int J Periodontics Restorative Dent. 2012 Apr;32(2):e41-50.